BRISC and BRCA1-A Complex Member 2

Preferred Label : BRISC and BRCA1-A Complex Member 2;

NCIt synonyms : BRCA1/BRCA2-Containing Complex, Subunit 4; BRCA1-A Complex Subunit BRE; Brain and Reproductive Organ-Expressed Protein; BRCA1/BRCA2-Containing Complex Subunit 45; BABAM2;

NCIt definition : BRISC and BRCA1-A complex member 2 (383 aa, 43 kDa) is encoded by the human BABAM2 gene. This protein is involved in binding to ubiquitinated histones.;

NCIt note : BRCA1-A complex subunit BRE specifically binds to histones H2A and H2AX at DNA lesion sites when lysine 63 is ubiquitinated. (UniProt);

Détails

Origin ID

C124107;

UMLS CUI

C1430133;

Automatic exact mappings (from CISMeF team)
- Brain and reproductive organ-expressed protein [OMIM gene]
OMIM relation
- Brain and reproductive organ-expressed protein [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- BABAM2 protein, human [MeSH Supplementary Concept]
- BABAM2 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- BABAM2 Gene [NCIt concept]
- DNA Repair Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Chromatin Remodeling Factor [NCIt concept]
gene_product_has_chemical_classification
- Protein Complex Subunit [NCIt concept]
gene_product_is_element_in_pathway
- Homologous Recombination Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Cycle Checkpoint [NCIt concept]
- DNA Repair [NCIt concept]
- Double Strand Break Repair [NCIt concept]
- Protein-Protein Interaction [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

Vous pouvez consulter :

recommendations
documents concerning education
documents for patients