CDKN2D wt Allele

Preferred Label : CDKN2D wt Allele;

NCIt synonyms : Cell Cycle Inhibitor, Nur77 Associating Protein Gene; Cyclin-Dependent Kinase Inhibitor 2D (p19, Inhibits CDK4) wt Allele; INK4D; p19; p19-INK4D;

NCIt definition : Human CDKN2D wild-type allele is located in the vicinity of 19p13 and is approximately 3 kb in length. This allele, which encodes cyclin-dependent kinase 4 inhibitor D protein, plays a role in the negative regulation of cyclin-dependent kinase activity.;

NCIt note : A fusion involving the CDKN2D gene and the WDFY2 gene may be associated with high-grade serous ovarian carcinoma. (COSMIC);

GenBank Accession Number : NM_079421;

Details

Origin ID

C122827;

UMLS CUI

C4049865;

Automatic exact mappings (from CISMeF team)
- Interleukin 23-alpha [OMIM gene]
- cyclin dependent kinase inhibitor 2A [ORDO Gene]
- cyclin dependent kinase inhibitor 2D [ORDO Gene]
- interleukin-23 complex [GO term]
OMIM relation
- Cyclin-dependent kinase inhibitor 2d [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 19p13 [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Beckwith-Wiedemann Syndrome [NCIt concept]
gene_is_element_in_pathway
- Cell Cycle Pathway [NCIt concept]
- Cyclin Regulation of Cell Cycle Pathway [NCIt concept]
- G2/M Checkpoint Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Cycle Process [NCIt concept]
- Cell Cycle Regulation Process [NCIt concept]
- Inhibition of Cell Proliferation [NCIt concept]
- Protein Dephosphorylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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