" /> Tavolimab - CISMeF





Preferred Label : Tavolimab;

NCIt synonyms : Tavolixizumab;

NCIt related terms : Anti-OX40 Monoclonal Antibody MEDI0562;

NCIt definition : An agonistic, humanized monoclonal antibody against receptor OX40 (CD134), with potential immunostimulatory activity. Upon administration, tavolimab selectively binds to and activates the OX40 receptor. OX40 receptor activation induces proliferation of memory and effector T-lymphocytes. In the presence of tumor-associated antigens (TAAs), this agent may promote an immune response against TAAs-expressing tumor cells. OX40, a cell surface glycoprotein and member of the tumor necrosis factor (TNF) receptor family, is expressed on T-lymphocytes and provides a co-stimulatory signal for the proliferation and survival of activated T-cells.;

UNII : 4LU9B48U4D;

CAS number : 1635395-25-3; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1635395-25-3 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : MEDI-0562;

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15/05/2024


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