SOCS2 wt Allele

Preferred Label : SOCS2 wt Allele;

NCIt synonyms : SSI-2; SOCS-2; Suppressor of Cytokine Signaling 2 wt Allele; Cish2; STATI2; CIS2; SSI2;

NCIt definition : Human SOCS2 wild-type allele is located within 12q and is approximately 14 kb in length. This allele, which encodes suppressor of cytokine signaling 2 protein, plays a role in the negative regulation of cytokine signaling pathways.;

NCIt note : Ensembl reports that the human SOCS2 gene is located in the vicinity of 12q22.; Expression is analyzed as part of the 17-gene leukemia stem cell scoring system (LSC17). (Nature. 2016; doi:10.1038/nature20598.);

GenBank Accession Number : AF037989;

Details

Origin ID

C116026;

UMLS CUI

C3890424;

Automatic exact mappings (from CISMeF team)
- SHOC2 leucine rich repeat scaffold protein [ORDO Gene]
- Suppressor of cytokine signaling 2 [OMIM gene]
OMIM relation
- Suppressor of cytokine signaling 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 12q [NCIt concept]
gene_is_element_in_pathway
- IL2-Mediated Signaling Pathway [NCIt concept]
- Insulin/Insulin Receptor Signaling Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
- Type II Diabetes Mellitus Pathway [NCIt concept]
gene_plays_role_in_process
- Cytokine Signaling [NCIt concept]
- Negative Regulation of Apoptosis [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients