MAX Gene-Associated Protein

Preferred Label : MAX Gene-Associated Protein;

NCIt synonyms : MAX Dimerization Protein 5; MGA;

NCIt definition : MAX gene-associated protein (3026 aa, 332 kDa) is encoded by the human MGA gene. This protein plays a role in the in the modulation of MYC and MAX-dependent gene transcription.;

NCIt note : MAX gene-associated protein binds to the 5'-AATTTCACACCTAGGTGTGAAATT-3' core sequence but can bind to E-box sequences when it dimerizes with MAX. (UniProt);

Details

Origin ID

C115318;

UMLS CUI

C3712788;

Automatic exact mappings (from CISMeF team)
- 3-methylglutaconic aciduria [ICD-11 More detail]
- Maltase-glucoamylase [OMIM gene]
- Max dimerization protein mga [OMIM gene]
OMIM relation
- Max dimerization protein mga [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- MGA protein, human [MeSH Supplementary Concept]
- MGA protein, human [MeSH concept]
gene_encodes_gene_product
- MGA Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- BHLH Protein [NCIt concept]
- DNA Binding Protein [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- bHLH Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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