" /> Genistein - CISMeF





Preferred Label : Genistein;

NCIt synonyms : Genestein; Genisteol; Prunetol; 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 4',5,7-Trihydroxyisoflavone;

NCIt related terms : 4',5, 7-Trihydroxyisoflavone;

NCIt definition : A soy-derived isoflavone and phytoestrogen with antineoplastic activity. Genistein binds to and inhibits protein-tyrosine kinase, thereby disrupting signal transduction and inducing cell differentiation. This agent also inhibits topoisomerase-II, leading to DNA fragmentation and apoptosis, and induces G2/M cell cycle arrest. Genistein exhibits antioxidant, antiangiogenic, and immunosuppressive activities. (NCI04);

Alternative definition : CRCH: An isoflavone with a hydroxyl group on the B-ring and a second hydroxyl group on the A-ring.; NCI-GLOSS: An isoflavone found in soy products. Soy isoflavones are being studied to see if they help prevent cancer.;

UNII : DH2M523P0H;

InChIKey : TZBJGXHYKVUXJN-UHFFFAOYSA-N;

CAS number : 446-72-0; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 446-72-0 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Unit used : mcg;

Chemical formula : C15H10O5;

NSC code : 36586;

ChEBI ID : CHEBI:28088;

Codes from synonyms : 04350; CDR0000046107; NSC0036586;

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15/05/2024


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