genistein - CISMeF

Preferred Label : genistein;

MeSH definition : An isoflavonoid derived from soy products. It inhibits PROTEIN-TYROSINE KINASE and topoisomerase-II (DNA TOPOISOMERASES, TYPE II); activity and is used as an antineoplastic and antitumor agent. Experimentally, it has been shown to induce G2 PHASE arrest in human and murine cell lines and inhibits PROTEIN-TYROSINE KINASE.;

MeSH synonym : genestein;

MeSH Related Number : 446-72-0 (Genistein);

Registry Number MeSH : 446-72-0;

Wikipedia link : https://en.wikipedia.org/wiki/Genistein;

Codes EINECS : 207-174-9;

Is substance : O;

UNII : DH2M523P0H;

InChIKey : TZBJGXHYKVUXJN-UHFFFAOYSA-N;

Details

Origin ID

D019833;

UMLS CUI

C0061202;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- genistein [Substance BNPC]
Currated CISMeF NLP mapping
- Genistein [LOINC component]
- Genistein [NCIt concept]
Pharmacological action(s)
- anticarcinogenic agents [MeSH Descriptor]
- phytoestrogens [MeSH Descriptor]
- protein kinase inhibitors [MeSH Descriptor]
Record concept(s)
- genistein [MeSH concept]
Related MeSH Supplementary Concept(s)
- 2'-hydroxy-genistein [MeSH Supplementary Concept]
- 3',8-dichlorogenistein [MeSH Supplementary Concept]
- 3'-hydroxy-genistein [MeSH Supplementary Concept]
- 4'-amino-6-hydroxyflavone [MeSH Supplementary Concept]
- 6,8-diprenylgenistein [MeSH Supplementary Concept]
- 6-carboxymethyl genistein [MeSH Supplementary Concept]
- 7-(4-(diethylamino)butoxy)-5-hydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one [MeSH Supplementary Concept]
- 7-O-(2,3,4,6-tetra-O-acetylgalactopyranosyl)-1-4-(6-O-acetylhex-2-enepyranosyl)genistein [MeSH Supplementary Concept]
- 7-difluoromethoxy-5,4'-dimethoxy-genistein [MeSH Supplementary Concept]
- 7-difluoromethoxyl-5,4'-di-n-octylgenistein [MeSH Supplementary Concept]
- 7-difluoromethyl-5,4'-dimethoxygenistein [MeSH Supplementary Concept]
- 8-(1,1-dimethylallyl)genistein [MeSH Supplementary Concept]
- 8-chlorogenistein [MeSH Supplementary Concept]
- 8-prenylgenistein [MeSH Supplementary Concept]
- EGF-genistein [MeSH Supplementary Concept]
- ITB 301 [MeSH Supplementary Concept]
- biochanin A [MeSH Supplementary Concept]
- genistein 4'7-O-dioleate [MeSH Supplementary Concept]
- genistein 7,4'-(bromo)butyrate [MeSH Supplementary Concept]
- genistein 7,4'-(nitrooxy)butyrate [MeSH Supplementary Concept]
- genistein combined polysaccharide [MeSH Supplementary Concept]
- genistein-17.1A immunoconjugate [MeSH Supplementary Concept]
- genistein-3'-sodium sulfonate [MeSH Supplementary Concept]
- genistein-4',7-diglucuronide [MeSH Supplementary Concept]
- genistein-7-glucuronide-4'-sulfate [MeSH Supplementary Concept]
- genistein-8-c-glucoside [MeSH Supplementary Concept]
Semantic type(s)
- Biologically Active Substance [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Genistein [NCIt concept]
- Genistein [LOINC component]
- genistein [Substance BNPC]

Keyword's position in hierarchy(ies) :

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