Neurogenin-1 - CISMeF

Preferred Label : Neurogenin-1;

NCIt synonyms : Neurogenic Differentiation Factor 3; Class A Basic Helix-Loop-Helix Protein 6; Neurogenic Basic-Helix-Loop-Helix Protein; bHLHa6; NGN-1; NEUROG1; NeuroD3;

NCIt definition : Neurogenin-1 (237 aa, 26 kDa) is encoded by the human NEUROG1 gene. This protein plays a role in both neuron differentiation and the regulation of gene expression.;

NCIt note : Neurogenin-1 activates transcription by binding to the E box (5'-CANNTG-3'). (UniProt);

Details

Origin ID

C105861;

UMLS CUI

C0537839;

Automatic exact mappings (from CISMeF team)
- Neurogenin 1 [OMIM gene]
OMIM relation
- Neurogenin 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- NEUROG1 protein, human [MeSH Supplementary Concept]
- NEUROG1 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- NEUROG1 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- BHLH Protein [NCIt concept]
- DNA Binding Protein [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- bHLH Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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