Zinc Finger E-Box-Binding Homeobox 1

Preferred Label : Zinc Finger E-Box-Binding Homeobox 1;

NCIt synonyms : Delta-Crystallin Enhancer Binding Factor 1; ZEB1; TCF-8; Zinc Finger Homeodomain Enhancer-Binding Protein; NIL-2-A Zinc Finger Protein; Negative Regulator of IL2; Transcription Factor 8;

NCIt definition : Zinc finger E-box-binding homeobox 1 (1124 aa, 124 kDa) is encoded by the human ZEB1 gene. This protein is involved in both the transcriptional repression of interleukin 2 and the positive regulation of neuronal differentiation.;

Details

Origin ID

C105607;

UMLS CUI

C4083254;

Automatic exact mappings (from CISMeF team)
- Zinc Finger E-box-Binding Homeobox 1 [MeSH Descriptor]
- Zinc Finger E-box-Binding Homeobox 1 [MeSH concept]
- Zinc finger e box-binding homeobox 1 [OMIM gene]
- corneal dystrophy, posterior polymorphous, 3 [MeSH concept]
- corneal dystrophy, posterior polymorphous, 3 [MeSH Supplementary Concept]
- posterior polymorphous corneal dystrophy 3 [DO Concept]
- zinc finger E-box binding homeobox 1 [ORDO Gene]
OMIM relation
- Zinc finger e box-binding homeobox 1 [OMIM gene]
See also inter- (CISMeF)
- Corneal dystrophy, posterior polymorphous, 3 [OMIM Phenotype]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
- ZEB1 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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