Zinc Finger E-box-Binding Homeobox 1

Preferred Label : Zinc Finger E-box-Binding Homeobox 1;

MeSH definition : A transcription factor characterized by N-terminal and C-terminal CYS2-HIS2 ZINC FINGERS separated by a homeobox. It represses the expression of E-CADHERIN to induce the EPITHELIAL-MESENCHYMAL TRANSITION. It also represses PROTO-ONCOGENE PROTEINS C-BCL-6; regulates the cell type-specific expression of SODIUM-POTASSIUM-EXCHANGING ATPASE; and promotes neuronal differentiation.;

MeSH synonym : Zinc Finger E box Binding Homeobox 1; NIL-2-A Zinc Finger Protein; NIL 2 A Zinc Finger Protein; TCF8 Protein; Zeb1 Transcription Factor; Transcription Factor, Zeb1; Transcription Factor 8;

Details

Origin ID

D000071799;

UMLS CUI

C3537279;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Zinc Finger E-Box-Binding Homeobox 1 [NCIt concept]
- Zinc finger e box-binding homeobox 1 [OMIM gene]
Record concept(s)
- Zinc Finger E-box-Binding Homeobox 1 [MeSH concept]
Related MeSH Supplementary Concept(s)
- ZEB1 protein, human [MeSH Supplementary Concept]
- ZEB1 protein, mouse [MeSH Supplementary Concept]
- ZEB1 protein, rat [MeSH Supplementary Concept]
- zeb1b protein, zebrafish [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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