Killer-Cell Immunoglobulin-Like Receptor

Preferred Label : Killer-Cell Immunoglobulin-Like Receptor;

NCIt synonyms : Killer Cell Immunoglobulin-Like Receptor; KIR; Killer Ig Receptor; CD158; CD158 Family; Killer-Cell Immunoglobulin-Like Receptor Family; Killer Ig-Like Receptor;

NCIt definition : A family of cell surface proteins found on natural killer cells that both interact with MHC class I molecules and modulate natural killer cell-mediated cytotoxicity.;

Details

Origin ID

C104678;

UMLS CUI

C0665952;

Biochemical function of gene products
- Killer Cell Immunoglobulin-Like Receptor 2DL1 [NCIt concept]
- Killer Cell Immunoglobulin-Like Receptor 2DL2 [NCIt concept]
- Killer Cell Immunoglobulin-Like Receptor 2DL3 [NCIt concept]
- Killer Cell Immunoglobulin-Like Receptor 2DS1 [NCIt concept]
- Killer Cell Immunoglobulin-Like Receptor 2DS3 [NCIt concept]
- Killer Cell Immunoglobulin-Like Receptor 2DS4 [NCIt concept]
- Killer Cell Immunoglobulin-Like Receptor 3DL1 [NCIt concept]
- Killer Cell Immunoglobulin-Like Receptor 3DL2 [NCIt concept]
- Killer Cell Immunoglobulin-Like Receptor 3DL3 [NCIt concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- receptors, KIR [MeSH concept]
- receptors, kir [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Immunoglobulin Family Gene [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
gene_product_has_structural_domain_or_motif
- Immunoglobulin Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell-Mediated Cytotoxicity [NCIt concept]
- Immune Cell Activation Process [NCIt concept]
is_target
- Anti-KIR Monoclonal Antibody IPH 2101 [NCIt concept]
- Lirilumab [NCIt concept]

Keyword's position in hierarchy(ies) :

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