Anti-KIR Monoclonal Antibody IPH 2101

Preferred Label : Anti-KIR Monoclonal Antibody IPH 2101;

NCIt synonyms : Anti-KIR Monoclonal Antibody 1-7F9;

NCIt related terms : IPH-2101;

NCIt definition : A human monoclonal antibody directed against the human inhibitory killer IgG-like receptor (KIR) with potential immunostimulating and antineoplastic activities. Anti-KIR monoclonal antibody IPH 2101 binds to the KIR receptor expressed on human natural killer (NK) cells, which may prevent KIR-mediated inhibition of NK cells and permit NK cell-mediated anti-tumor cytotoxicity. KIRs are surface glycoproteins that bind to major histocompatibility complex (MHC)/human leukocyte antigen (HLA) class I subtypes on target cells; binding of KIRs inhibits NK cell-mediated cytotoxicity.;

UNII : 5Q686XLG8L;

CAS number : 1000676-42-5;

Molecule name : 1-7F9; IPH 2101; IPH-2101;

Codes from synonyms : 260;

Details

Origin ID

C78464;

UMLS CUI

C2703118;

Currated CISMeF NLP mapping
- IPH-2101 [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- IPH-2101 [MeSH Supplementary Concept]
- IPH-2101 [MeSH concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Killer-Cell Immunoglobulin-Like Receptor [NCIt concept]

Keyword's position in hierarchy(ies) :

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