WNT16 wt Allele

Preferred Label : WNT16 wt Allele;

NCIt synonyms : Wingless-Type MMTV Integration Site Family, Member 16b Gene; Wingless-Type MMTV Integration Site Family, Member 16 wt Allele;

NCIt definition : Human WNT16 wild-type allele is located in the vicinity of 7q31 and is approximately 16 kb in length. This allele, which encodes protein Wnt-16, plays a role in both receptor binding and ligand-mediated signaling.;

NCIt note : Overexpression of WNT16 following chemotherapy for prostate carcinoma may be associated with resistance to further chemotherapeutics. (Nature Medicine 2012; 18:1359-1368.);

GenBank Accession Number : AF152584;

Details

Origin ID

C102966;

UMLS CUI

C3541410;

OMIM relation
- Wingless-type mmtv integration site family, member 16 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 7q31 [NCIt concept]
gene_is_element_in_pathway
- Basal Cell Carcinoma Pathway [NCIt concept]
- Hedgehog Signaling Pathway [NCIt concept]
- Melanogenesis Pathway [NCIt concept]
- WNT Signaling Pathway BioCarta [NCIt concept]
- Wnt Signaling Pathway KEGG [NCIt concept]
gene_plays_role_in_process
- Induction of Cell Senescence [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Keratinocyte Differentiation [NCIt concept]
- Negative Regulation of Apoptosis [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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