Cyclin-Dependent Kinase 5 Activator 1

Preferred Label : Cyclin-Dependent Kinase 5 Activator 1;

NCIt synonyms : CDK5 Activator 1; TPKII Regulatory Subunit; Cyclin-Dependent Kinase 5 Regulatory Subunit 1;

NCIt definition : Cyclin-dependent kinase 5 activator 1 (307 aa, 34 kDa) is encoded by the human CDK5R1 gene. This protein is involved in the modulation of both kinase activity and neuronal development.;

NCIt note : Cyclin-dependent kinase 5 activator 1 is cleaved to form p35 or p25. (UniProt);

Details

Origin ID

C102497;

UMLS CUI

C3640794;

OMIM relation
- Cyclin-dependent kinase 5, regulatory subunit 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
gene_encodes_gene_product
- CDK5R1 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_expressed_in_tissue
- Brain [NCIt concept]
- Neuron [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
gene_product_is_element_in_pathway
- Alzheimer's Disease Pathway BioCarta [NCIt concept]
- CK1/CDK5 Regulation Pathway [NCIt concept]
- Glucocorticoid Receptor Regulatory Network [NCIt concept]
- LIS1 Pathway [NCIt concept]
- Lissencephaly-1 Gene in Neuronal Migration and Development [NCIt concept]
- MAP Kinase Downregulation Pathway [NCIt concept]
- NTRK1/MAPK Signaling Pathway [NCIt concept]
- Rac1 Cell Motility Signaling Pathway [NCIt concept]
- Reelin Signaling Pathway PID [NCIt concept]
gene_product_plays_role_in_biological_process
- Neural Development [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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