Carbohydrate-Responsive Element-Binding Protein

Preferred Label : Carbohydrate-Responsive Element-Binding Protein;

NCIt synonyms : Williams-Beuren Syndrome Chromosomal Region 14 Protein; WS Basic-Helix-Loop-Helix Leucine Zipper Protein; Class D Basic Helix-Loop-Helix Protein 14; MLX Interactor; bHLHd14; WS-bHLH; ChREBP; MLX-Interacting Protein-Like; MLXIPL;

NCIt definition : Carbohydrate-responsive element-binding protein (852 aa, 93 kDa) is encoded by the human MLXIPL gene. This protein plays a role in transcriptional regulation.;

NCIt note : Carbohydrate-responsive element-binding protein binds to the canonical and non-canonical E box sequences 5'-CACGTG-3'. (UniProt);

Details

Origin ID

C102476;

UMLS CUI

C3539691;

OMIM relation
- Mlx-interacting protein-like [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- MLXIPL Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_expressed_in_tissue
- Cerebellum [NCIt concept]
- Heart [NCIt concept]
- Hepatic Tissue [NCIt concept]
- Intestine [NCIt concept]
- Renal Tissue [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
gene_product_has_chemical_classification
- BHLH Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- bHLH Domain [NCIt concept]
gene_product_is_element_in_pathway
- ChREBP Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cholesterol Homeostasis [NCIt concept]
- DNA Binding [NCIt concept]
- Glycolysis Induction [NCIt concept]
- Homeostatic Process [NCIt concept]
- Signal Transduction [NCIt concept]
- Stimulation of Cell Proliferation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients