Preferred Label : zolbetuximab;
MeSH note : in Phase IIa trial 1/14 for treatment of advanced gastroesophageal cancer (clincaltrials.gov:
NCT00909025);
CISMeF synonym : claudiximab;
MeSH hyponym : IMAB-362;
UNII : TF5MPQ8WGY;
Origin ID : C585662;
UMLS CUI : C2827697;
ATC code(s)
Currated CISMeF NLP mapping
MeSH term(s) associated for indexing
Record concept(s)
Semantic type(s)
UMLS correspondences (same concept)
https://www.has-sante.fr/jcms/p_3576557/fr/vyloy-zolbetuximab-adenocarcinome-gastrique-et-de-la-jonction-oesogastrique
2025
false
false
false
France
antineoplastic combined chemotherapy protocols
treatment outcome
insurance, health, reimbursement
adult
Fluoropyrimidine
platinum salt, nos
Gastric Adenocarcinoma
stomach neoplasms
Gastroesophageal Junction Adenocarcinoma
esophageal neoplasms
HER2/Neu Negative
CLDN18.2 Positive
infusions, intravenous
zolbetuximab
evaluation of the transparency committee
zolbetuximab
adenocarcinoma
---
https://www.ema.europa.eu/en/medicines/human/EPAR/vyloy
2025
false
false
false
Netherlands
French
English
syndication feed
summary of product characteristics
package leaflet
drug evaluation
treatment outcome
zolbetuximab
zolbetuximab
orphan drug production
zolbetuximab
drug approval
europe
Antineoplastic Agents, Immunological
Antineoplastic Agents, Immunological
infusions, intravenous
antibodies, monoclonal
antibodies, monoclonal
stomach neoplasms
esophageal neoplasms
adenocarcinoma
antineoplastic combined chemotherapy protocols
Metastatic Gastric Adenocarcinoma
Locally Advanced Unresectable Gastric Adenocarcinoma
Locally Advanced Unresectable Gastroesophageal Junction Adenocarcinoma
Metastatic Gastroesophageal Junction Adenocarcinoma
CLDN18.2 Positive
HER2/Neu Negative
product surveillance, postmarketing
adult
aged
CLDN18 protein, human
Anti-claudin18.2 Monoclonal Antibody
pregnancy
breast feeding
drug evaluation, preclinical
---
https://www.has-sante.fr/jcms/p_3594155/fr/vyloy-zolbetuximab-adenocarcinome-gastrique-et-de-la-jonction-oesogastrique
2025
false
false
false
France
stomach neoplasms
esophageal neoplasms
treatment outcome
insurance, health, reimbursement
zolbetuximab
infusions, intravenous
Antineoplastic Agents, Immunological
antineoplastic combined chemotherapy protocols
adult
Gastroesophageal Junction Adenocarcinoma
Gastric Adenocarcinoma
CLDN18.2 Positive
HER2/Neu Negative
evaluation of the transparency committee
adenocarcinoma
zolbetuximab
esophagogastric junction
---