Preferred Label : sonidegib;
MeSH note : specific Smoothened/Smo antagonist;
CISMeF synonym : N-(6-((2S,6R)-2,6-dimethylmorpholino)pyridin-3-yl)-2-methyl-4'-(trifluoromethoxy)biphenyl-3-carboxamide; LDE225;
MeSH synonym : (1,1'-Biphenyl)-3-carboxamide, N-(6-((2R,6S)-2,6-dimethyl-4-morpholinyl)-3-pyridinyl)-2-
methyl-4'-(trifluoromethoxy)-, rel-;
Related MeSH term : NVP-LDE225;
Is substance : O;
UNII : 0RLU3VTK5M;
Origin ID : C561435;
UMLS CUI : C3886731;
ATC code(s)
Currated CISMeF NLP mapping
MeSH term(s) associated for indexing
Record concept(s)
Semantic type(s)
UMLS correspondences (same concept)
https://ansm.sante.fr/tableau-marr/sonidegib
2024
false
false
false
France
French
risk management
sonidegib
teratogens
pregnancy
abnormalities, drug-induced
contraception
pregnancy tests
antineoplastic agents
fetal death
patient education handout
guidelines for drug use
guideline
sonidegib
biphenyl compounds
pyridines
---
http://www.has-sante.fr/portail/jcms/c_2655911/fr/odomzo
https://www.has-sante.fr/portail/jcms/c_2655911/fr/odomzo-sonidegib-inhibiteur-de-hedgehog
2016
false
false
false
France
French
evaluation of the transparency committee
treatment outcome
sonidegib
sonidegib
sonidegib
adult
carcinoma, basal cell
Locally Advanced Malignant Neoplasm
administration, oral
antineoplastic agents
antineoplastic agents
insurance, health, reimbursement
Hedgehog Signaling Pathway
Response Rate
survival analysis
Odomzo
guidelines for drug use
sonidegib
sonidegib
biphenyl compounds
pyridines
biphenyl compounds
pyridines
sonidegib
biphenyl compounds
pyridines
---
https://www.ema.europa.eu/medicines/human/EPAR/Odomzo
2015
false
false
false
United Kingdom
French
English
treatment outcome
syndication feed
summary of product characteristics
package leaflet
drug evaluation
drug approval
europe
sonidegib
sonidegib
adult
Unresectable Malignant Neoplasm
Locally Advanced Malignant Neoplasm
carcinoma, basal cell
administration, oral
Hedgehog Signaling Pathway
drug monitoring
product surveillance, postmarketing
drug interactions
pregnancy
contraception
teratogens
breast feeding
survival analysis
drug evaluation, preclinical
sonidegib
sonidegib
sonidegib
biphenyl compounds
pyridines
biphenyl compounds
pyridines
---