Preferred Label : netupitant;

MeSH note : orally active neurokinin-1 receptor antagonist; structure in first source;

MeSH synonym : benzeneacetamide, N, alpha, alpha-trimethyl-N-(4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinyl)-3,5-bis(trifluoromethyl)-; 2-(3,5-bis(trifluoromethyl)phenyl)-N-methyl-N-(4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridin-3-yl)-2-methylpropanamide; 2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethyl-N-(4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridin-3-yl)propanamide;

MeSH hyponym : netupitant hydrochloride; benzeneacetamide, N, alpha,alpha-trimethyl-N-(4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinyl)-3,5-bis(trifluoromethyl)-, hydrochloride (1:2); RO-67-3189 000; RO 67-3189 000; RO-67-3189; RO 673189000;

MeSH Related Number : OA7JCO20ZP;

Is substance : O;

UNII : 7732P08TIR;

InChIKey : WAXQNWCZJDTGBU-UHFFFAOYSA-N;

Details


Main resources

You can consult :


http://www.has-sante.fr/portail/jcms/c_2755488/fr/akynzeo
https://www.has-sante.fr/portail/jcms/c_2755488/fr/akynzeo-palonosetron-netupitant-setron-en-association
2017
false
false
false
France
French
treatment outcome
drug combinations
netupitant
palonosetron, combinations
palonosetron hydrochloride
nausea
nausea
antineoplastic agents
vomiting
vomiting
administration, oral
serotonin 5-HT3 receptor antagonists
Neurokinin-1 receptor antagonists
netupitant, palosentron drug combination
evaluation of the transparency committee
insurance, health, reimbursement
guidelines for drug use
pyridines
isoquinolines
quinuclidines
Palonosetron

---
https://www.ema.europa.eu/medicines/human/EPAR/Akynzeo
2015
false
false
false
United Kingdom
French
English
treatment outcome
syndication feed
summary of product characteristics
package leaflet
drug evaluation
drug combinations
drug approval
netupitant
netupitant
palonosetron, combinations
palonosetron hydrochloride
palonosetron hydrochloride
Drug-Related side effects and adverse reactions
nausea
nausea
antineoplastic agents
vomiting
vomiting
administration, oral
serotonin 5-HT3 receptor antagonists
serotonin 5-HT3 receptor antagonists
Neurokinin-1 receptor antagonists
Neurokinin-1 receptor antagonists
product surveillance, postmarketing
pregnancy
breast feeding
drug interactions
drug evaluation, preclinical
netupitant, palosentron drug combination
netupitant, palosentron drug combination
pyridines
pyridines
isoquinolines
quinuclidines
isoquinolines
quinuclidines
Palonosetron
Palonosetron

---
Nous contacter.
18/05/2024


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