Palonosetron - CISMeF

Preferred Label : Palonosetron;

MeSH definition : Isoquinoline and quinuclidine derivative that acts as a 5-HT3 RECEPTOR antagonist. It is used in the prevention of nausea and vomiting induced by cytotoxic chemotherapy, and for the prevention of post-operative nausea and vomiting.;

MeSH synonym : 2-QHBIQO;

MeSH hyponym : Palonosetron, (3R)-; RS 25259 198; RS 25259198; RS-25259-198; RS25259198; RS 25233 198; RS 25233198; RS-25233-198; RS25233198; RS-25259; RS25259; RS 25259 197; RS 25259197; RS-25259-197; RS25259197; RS 25233 197; RS 25233197; RS-25233-197; RS25233197;

MeSH CAS label : 1H-Benz(de)isoquinolin-1-one, 2-((3S)-1-azabicyclo(2.2.2)oct-3-yl)-2,3,3a,4,5,6-hexahydro-, (3aS)-;

MeSH Related Number : 135729-61-2 (Palonosetron); 135729-73-6 ((S-(R*,S*))-isomer); 149653-99-6 ((R-(R*,R*))-isomer); 149654-00-2 ((R-(R*,S*))-isomer); 23310D4I19; 2UCB21ER4V;

Wikipedia link : https://en.wikipedia.org/wiki/Palonosetron;

UNII : 5D06587D6R;

Details

Origin ID

D000077924;

UMLS CUI

C0220578;

ATC code(s)
- palonosetron [ATC Code]
- palonosetron, combinations [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Pharmacological action(s)
- antiemetics [MeSH Descriptor]
- peripheral nervous system agents [MeSH Descriptor]
- serotonin 5-HT3 receptor antagonists [MeSH Descriptor]
Record concept(s)
- 2-(1-azabicyclo(2.2.2)oct-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benz(de)isoquinolin-1-one [MeSH concept]
- RS 25233-197 [MeSH concept]
- RS 25233-198 [MeSH concept]
- RS 25259 [MeSH concept]
- RS 25259-197 [MeSH concept]
- RS 25259-198 [MeSH concept]
- aloxi [MeSH concept]
- palonosetron [MeSH concept]
- palonosetron hydrochloride [MeSH concept]
- palonosetron, (R-(R*,R*))-isomer [MeSH concept]
- palonosetron, (R-(R*,S*))-isomer [MeSH concept]
- palonosetron, (S-(R*,S*))-isomer [MeSH concept]
See also inter- (CISMeF)
- Product containing palonosetron (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to BTNT
- Palonosetron Hydrochloride [NCIt concept]
- Palonosetron hydrochloride (substance) [SNOMED CT concept]
- palonosetron [ATC Code]
- palonosetron hydrochloride [International Nonproprietary Name]

Keyword's position in hierarchy(ies) :

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