Preferred Label : eculizumab;
MeSH note : binds terminal complement protein C5;
CISMeF synonym : alexion brand of eculizumab; soliris;
MeSH hyponym : H5G1.1VHC H5G1.1VLC; H5G1.1; H5G1-1; H5G11;
Is substance : O;
UNII : A3ULP0F556;
Origin ID : C481642;
UMLS CUI : C1541483;
ATC code(s)
- Currated CISMeF NLP mapping
- Exact mapping(s) to DCI
- MeSH term(s) associated for indexing
- Pharmacological action(s)
- Record concept(s)
- See also inter- (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
https://ansm.sante.fr/tableau-marr/eculizumab-2
2024
false
false
false
France
French
risk management
eculizumab
eculizumab
eculizumab
guidelines for drug use
patient education handout
patients guideline
antibiotic prophylaxis
infusions, intravenous
Infections
sepsis
Drug-Related side effects and adverse reactions
meningococcal infections
vaccination
meningococcal vaccines
---
https://ansm.sante.fr/tableau-marr/eculizumab-1
2024
false
false
false
France
French
risk management
guidelines for drug use
eculizumab
eculizumab
continuity of patient care
Drug-Related side effects and adverse reactions
vaccination
patients guideline
Infections
sepsis
meningococcal infections
risk
---
https://www.has-sante.fr/jcms/p_3517560/fr/soliris-eculizumab-myasthenie
2024
false
false
false
France
eculizumab
generalised myasthenia gravis with anti-acetylcholine receptor antibody
treatment outcome
child
Acetylcholine receptor antibody (substance)
infusions, intravenous
evaluation of the transparency committee
eculizumab
myasthenia gravis
---
https://ansm.sante.fr/tableau-marr/eculizumab
2024
false
false
false
France
French
risk management
guidelines for drug use
eculizumab
eculizumab
continuity of patient care
drug monitoring
patient safety
sepsis
meningococcal infections
risk
vaccination
antibiotic prophylaxis
adult
child
infant
patients guideline
patient education handout
Drug-Related side effects and adverse reactions
meningococcal vaccines
---
https://www.ema.europa.eu/en/medicines/human/EPAR/epysqli
2023
false
false
false
Netherlands
French
English
treatment outcome
syndication feed
summary of product characteristics
package leaflet
drug evaluation
drug approval
europe
eculizumab
eculizumab
eculizumab
biosimilar pharmaceuticals
hemoglobinuria, paroxysmal
adult
child
pregnancy
breast feeding
drug interactions
product surveillance, postmarketing
infusions, intravenous
drug evaluation, preclinical
---
https://www.has-sante.fr/jcms/p_3427913/fr/soliris-eculizumab-syndrome-hemolytique-et-uremique-atypique-shua
2023
false
false
false
France
treatment outcome
insurance, health, reimbursement
eculizumab
infusions, intravenous
adult
child
evaluation of the transparency committee
Atypical Hemolytic Uremic Syndrome
eculizumab
---
https://www.ema.europa.eu/en/medicines/human/EPAR/bekemv
2023
false
false
false
Netherlands
French
English
treatment outcome
syndication feed
summary of product characteristics
package leaflet
drug evaluation
drug approval
europe
eculizumab
eculizumab
eculizumab
biosimilar pharmaceuticals
adult
adolescent
child
hemoglobinuria, paroxysmal
infusions, intravenous
drug interactions
pregnancy
breast feeding
drug evaluation, preclinical
---
https://www.hcsp.fr/explore.cgi/avisrapportsdomaine?clefr=1175
2022
France
public health guidelines
eculizumab
judgment
complement inhibitor, nos
complement inactivating agents
ravulizumab
patients
eculizumab
bacterial infectious disease, nos
Complement
eculizumab
Infectious disease
has patient
bacterial infections
ravulizumab
prophylactic treatment, nos
---
https://www.hcsp.fr/explore.cgi/avisrapportsdomaine?clefr=959
2020
false
false
false
France
Invasive meningococcal disease (disorder)
antibiotic prophylaxis
vaccination
meningococcal vaccines
pneumococcal vaccines
haemophilus vaccines
haemophilus infections
pneumococcal infections
immunocompromised host
immunization schedule
adult
child
penicillin V
public health guidelines
eculizumab
meningococcal infections
ravulizumab
antibodies, monoclonal, humanized
---
https://www.has-sante.fr/jcms/p_3202348/fr/soliris
2020
false
false
false
France
insurance, health, reimbursement
adult
neuromyelitis optica
Anti-aquaporin-4 antibody
treatment outcome
eculizumab
evaluation of the transparency committee
eculizumab
antibodies, monoclonal, humanized
---
https://www.hc-sc.gc.ca/dhp-mps/medeff/reviews-examens/soliris-bexsero-fra.php
2016
false
false
false
Canada
French
pharmacovigilance note
educational measurement
hemoglobins
vaccinia
risk assessment
vaccination, nos
4CMenB vaccine
neisseria meningitidis
plural
eculizumab
hemoglobin a2prime
has patient
vaccination
vaccine, nos
hemoglobin, nos
hemolysis, nos
hemolysis
asthenia
vaccines
hemoglobin a2
treaties
vaccinia, nos
eculizumab
hemoglobin a3
patients
meningococcus vaccination
vaccinia
international cooperation
meningococcal vaccines
antibodies, monoclonal, humanized
---
https://canadiensensante.gc.ca/recall-alert-rappel-avis/hc-sc/2016/60752a-fra.php
2016
false
false
false
Canada
French
pharmacovigilance note
risk assessment
hemolysis
canada
eculizumab
eculizumab
vaccination
meningococcal vaccines
meningococcus B, multicomponent vaccine
meningococcal infections
neisseria meningitidis, serogroup B
Eculizumab 10mg/mL injection solution 30mL vial (product)
Atypical Hemolytic Uremic Syndrome
paroxysmal nocturnal hemoglobinuria
complement inactivating agents
hemoglobinuria, paroxysmal
antibodies, monoclonal, humanized
---
http://www.hcsp.fr/explore.cgi/avisrapportsdomaine?clefr=447
http://www.hcsp.fr/Explore.cgi/Telecharger?NomFichier=hcspa20140710_solirisactuarecosvaccantibiopro.pdf
2014
false
false
true
France
French
public health guidelines
meningococcal infections
meningococcal vaccines
infant
child
adult
antibiotic prophylaxis
anti-bacterial agents
antibodies, monoclonal, humanized
eculizumab
antibiotic therapy
---
http://www.has-sante.fr/portail/jcms/c_1319245/soliris
http://www.has-sante.fr/portail/display.jsp?id=c_605768
http://www.has-sante.fr/portail/jcms/c_1623651/fr/soliris
2013
France
French
antibodies, monoclonal, humanized
eculizumab
antibodies, monoclonal
orphan drug production
infusions, intravenous
complement inactivating agents
hemoglobinuria, paroxysmal
adult
aged
treatment outcome
eculizumab
antibodies, monoclonal
hemolytic-uremic syndrome
evaluation of the transparency committee
---
http://www.hcsp.fr/explore.cgi/avisrapportsdomaine?clefr=305
http://www.hcsp.fr/explore.cgi/hcspa20121109_antibiovaccsoliris.pdf
2012
France
French
practice guideline
antibiotic prophylaxis
antibodies, monoclonal, humanized
eculizumab
meningococcal vaccines
meningococcal infections
adult
child
---
https://www.ema.europa.eu/medicines/human/EPAR/Soliris
2012
United Kingdom
French
English
syndication feed
eculizumab
eculizumab
orphan drug production
drug evaluation
antibodies, monoclonal
treatment outcome
hemoglobinuria, paroxysmal
antibodies, monoclonal
antibodies, monoclonal, humanized
antibodies, monoclonal, humanized
eculizumab
antibodies, monoclonal
antibodies, monoclonal
drug evaluation
package leaflet
summary of product characteristics
---
http://www.has-sante.fr/portail/jcms/c_1343887/soliris-eculizumab-anticorps-monoclonal-anti-c5
http://www.has-sante.fr/portail/jcms/c_1343886/soliris-synthese-19092012-ct12290
2012
France
French
adult
child
rare diseases
hemolytic-uremic syndrome
eculizumab
orphan drug production
infusions, intravenous
adolescent
antibodies, monoclonal, humanized
guidelines for drug use
evaluation of the transparency committee
eculizumab
---
http://revmed.ch/RMS/2006/RMS-81/2302
2006
France
French
antibodies, monoclonal
antibodies, monoclonal, humanized
eculizumab
journal article
---
