pimecrolimus - CISMeF

Preferred Label : pimecrolimus;

MeSH note : an ascomycin derivative; mechanism of action involves calcineurin inhibition, blockage of T cell activation, blocking signal transduction pathways in T cells, and inhibition of the synthesis of inflammatory cytokines, specifically Th1- and Th2-type cytokines;

CISMeF synonym : ASM 981; SDZ ASM 981; elidel; novartis brand of pimecrolimus;

MeSH synonym : 33-epi-chloro-33-desoxyascomycin;

MeSH hyponym : SDZ-ASM-981;

Is substance : O;

UNII : 7KYV510875;

InChIKey : KASDHRXLYQOAKZ-XDSKOBMDSA-N;

Details

Origin ID

C117268;

UMLS CUI

C1099414;

ATC code(s)
- pimecrolimus [ATC Code]
Currated CISMeF NLP mapping
- Pimecrolimus [NCIt concept]
- Pimecrolimus (substance) [SNOMED CT concept]
- Product containing pimecrolimus (medicinal product) [SNOMED CT concept]
- pimecrolimus [ATC Code]
MeSH indexing information
- calcineurin [MeSH Descriptor]
- peptidylprolyl isomerase [MeSH Descriptor]
MeSH term(s) associated for indexing
- tacrolimus [MeSH Descriptor]
Pharmacological action(s)
- Calcineurin Inhibitors [MeSH Descriptor]
- anti-inflammatory agents, non-steroidal [MeSH Descriptor]
- dermatologic agents [MeSH Descriptor]
- immunosuppressive agents [MeSH Descriptor]
Record concept(s)
- ASM 981 [MeSH concept]
- SDZ ASM 981 [MeSH concept]
- elidel [MeSH concept]
- pimecrolimus [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Pimecrolimus [NCIt concept]
- Pimecrolimus (substance) [SNOMED CT concept]
- Product containing pimecrolimus (medicinal product) [SNOMED CT concept]
- pimecrolimus [ATC Code]

Keyword's position in hierarchy(ies) :

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