matk protein, mouse

Preferred Label : matk protein, mouse;

MeSH note : phosphorylates C-terminal conserved Tyr of Src family members; from mouse brain; has 52% identity with mouse Csk; could play a significant role in the signal transduction of hematopoietic cells; may regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site; it may play an inhibitory role in the control of T-cell proliferation; amino acid sequence given in first source; GenBank U05210; RefSeq NM_010768;

CISMeF synonym : bhk (kinase);

MeSH synonym : Ctk (kinase); Csk-like protein-tyrosine kinase; Ntk (kinase); megakaryocyte-associated tyrosine kinase, mouse; csk-type protein-tyrosine kinase;

Registry Number MeSH : EC 2.7.1.-;

Is substance : O;

Details

Origin ID

C086603;

UMLS CUI

C0253479;

Automatic exact mappings (from CISMeF team)
- Cyclin-Dependent Kinase 16 [NCIt concept]
- G Protein-Coupled Receptor Kinase [NCIt concept]
- G Protein-Coupled Receptor Kinase 4 [NCIt concept]
- G Protein-Coupled Receptor Kinase 5 [NCIt concept]
- G Protein-Coupled Receptor Kinase 6 [NCIt concept]
- G Protein-Coupled Receptor Kinase 7 [NCIt concept]
- Megakaryocyte-Associated Tyrosine-Protein Kinase [NCIt concept]
- Serine/Threonine-Protein Kinase Chk1 [NCIt concept]
- Serine/Threonine-Protein Kinase PAK 6 [NCIt concept]
MeSH term(s) associated for indexing
- proto-oncogene proteins pp60(c-src) [MeSH Descriptor]
Record concept(s)
- bhk (kinase) [MeSH concept]
- matk protein, mouse [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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