icatibant - CISMeF

Preferred Label : icatibant;

MeSH note : an antiasthmatic agent; a potent bradykinin (B2) receptor antagonist; WIN 65365 is an L-Tic(7) stereoisomer, exhibits 2000-fold lower binding affinity than HOE-140 to the bradykinin receptor;

CISMeF synonym : JE 049; JE049 compound; WIN 65365;

MeSH synonym : D-Arg(Hyp(3)-Thi(5)-D-Tic(7)-Oic(8))BK;

MeSH hyponym : WIN-65365; Hoechst-140; Hoechst 140; HOE-140; HOE140; JE-049; Firazyr; HOE 140; D-Arg(Hyp(3)-Thi(5)-L-Tic(7)-Oic(8))BK;

MeSH Related Number : icatibant acetate; 130308-48-4 (icatibant); 325O8467XK;

Registry Number MeSH : 130308-48-4;

Related CAS MeSH : 138614-30-9 (icatibant acetate);

related registry number list (CISMeF) : 138614-30-9 (acetate);

Is substance : O;

UNII : 7PG89G35Q7;

InChIKey : QURWXBZNHXJZBE-SKXRKSCCSA-N;

Details

Origin ID

C065679;

UMLS CUI

C0246269;

ATC code(s)
- icatibant [ATC Code]
CISMeF manual mappings
- Icatibant (substance) [SNOMED CT concept]
- icatibant [Substance BNPC]
MeSH indexing information
- receptors, bradykinin [MeSH Descriptor]
MeSH term(s) associated for indexing
- bradykinin [MeSH Descriptor]
Pharmacological action(s)
- Bradykinin B2 Receptor Antagonists [MeSH Descriptor]
- adrenergic beta-antagonists [MeSH Descriptor]
- anti-inflammatory agents, non-steroidal [MeSH Descriptor]
Record concept(s)
- JE 049 [MeSH concept]
- WIN 65365 [MeSH concept]
- icatibant [MeSH concept]
- icatibant acetate [MeSH concept]
See also inter- (CISMeF)
- Product containing icatibant (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Icatibant [NCIt concept]
- Icatibant (substance) [SNOMED CT concept]
- Product containing icatibant (medicinal product) [SNOMED CT concept]
- icatibant [ATC Code]
- icatibant [Substance BNPC]
Validated automatic mappings to BTNT
- Icatibant Acetate [NCIt concept]
- icatibant [ATC Code]

Keyword's position in hierarchy(ies) :

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