invariant chain

Preferred Label : invariant chain;

MeSH note : noncovalently associated with class II antigens, alpha & beta chain complex; involved in the regulation of malignant cell Ia function; Iip31 and Iip35 (previosly called Iip33) were synthesized by using alternative initiator methionines;

CISMeF synonym : Iip35; CLIP peptide; Ii76-92; ii IGC; Ii-Key; LN 2 antigen; Iip31; Iip33;

MeSH synonym : class II-associated invariant chain; Ia-associated invariant chain; CD74 antigen;

MeSH hyponym : Ii invariant glycoprotein complex; LN-2 antigen;

Is substance : O;

Details

Origin ID

C045084;

UMLS CUI

C0063356;

Automatic exact mappings (from CISMeF team)
- CD74 molecule [HGNC gene]
- Cd74 antigen [OMIM gene]
- HLA Class II Histocompatibility Antigen Gamma Chain [NCIt concept]
Currated CISMeF NLP mapping
- CD74 [LOINC component]
- Lymphocyte antigen CD74 (substance) [SNOMED CT concept]
- lymphocyte antigen cd74 [SNOMED Notion]
MeSH indexing information
- antigens, cd [MeSH Descriptor]
- antigens, neoplasm [MeSH Descriptor]
- molecular chaperones [MeSH Descriptor]
- neoplasm proteins [MeSH Descriptor]
MeSH term(s) associated for indexing
- antigens, differentiation, B-Lymphocyte [MeSH Descriptor]
- histocompatibility antigens class ii [MeSH Descriptor]
Record concept(s)
- CLIP peptide [MeSH concept]
- Ii-Key [MeSH concept]
- Ii76-92 [MeSH concept]
- Iip31 [MeSH concept]
- Iip33 [MeSH concept]
- Iip35 [MeSH concept]
- LN 2 antigen [MeSH concept]
- ii IGC [MeSH concept]
- invariant chain [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- CD74 [LOINC component]
- Lymphocyte antigen CD74 (substance) [SNOMED CT concept]
- lymphocyte antigen cd74 [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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