rho guanine nucleotide exchange factors

Preferred Label : rho guanine nucleotide exchange factors;

MeSH definition : Signaling proteins which function as master molecular switches by activating Rho GTPases through conversion of guanine nucleotides. Rho GTPases in turn control many aspects of cell behavior through the regulation of multiple downstream signal transduction pathways.;

MeSH hyponym : rho guanine nucleotide exchange factor p115; rho guanine nucleotide exchange factor 7; rho guanine nucleotide exchange factor 6; ARHGEF1; RhoGEF; p115 RhoGEF; RhoGEF, p115; Rho Guanine Nucleotide Exchange Factor (GEF) 1; p115RhoGEF; PAK-Interacting Exchange Factor beta; PAK Interacting Exchange Factor beta; Cool-1 Protein; Cool 1 Protein; Protein, Cool-1; beta PIX Protein; PIX Protein, beta; Protein, beta PIX; betaPIX Protein; Protein, betaPIX;

Is substance : O;

Details

Origin ID

D064067;

UMLS CUI

C3658359;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- ARHGEF1 Gene [NCIt concept]
- ARHGEF1 wt Allele [NCIt concept]
- Rac/Cdc42 guanine nucleotide exchange factor 6 [ORDO Gene]
- Rac/Cdc42 guanine nucleotide exchange factor 6 [HGNC gene]
- Rho Guanine Nucleotide Exchange Factor 1 [NCIt concept]
- Rho Guanine Nucleotide Exchange Factor 28 [NCIt concept]
- Rho Guanine Nucleotide Exchange Factor 7 [NCIt concept]
- Rho guanine nucleotide exchange factor 1 [OMIM gene]
- Rho guanine nucleotide exchange factor 28 [OMIM gene]
- Rho guanine nucleotide exchange factor 6 [OMIM gene]
- Rho guanine nucleotide exchange factor 7 [OMIM gene]
- Rho guanine nucleotide exchange factor 7 [HGNC gene]
- Rho guanyl-nucleotide exchange factor activity [GO term]
Record concept(s)
- rho guanine nucleotide exchange factor 6 [MeSH concept]
- rho guanine nucleotide exchange factor 7 [MeSH concept]
- rho guanine nucleotide exchange factor p115 [MeSH concept]
- rho guanine nucleotide exchange factors [MeSH concept]
Related MeSH Supplementary Concept(s)
- ARHGEF1 protein, human [MeSH Supplementary Concept]
- ARHGEF10 protein, human [MeSH Supplementary Concept]
- ARHGEF10 protein, mouse [MeSH Supplementary Concept]
- ARHGEF10L protein, human [MeSH Supplementary Concept]
- ARHGEF11 protein, human [MeSH Supplementary Concept]
- ARHGEF11 protein, mouse [MeSH Supplementary Concept]
- ARHGEF12 protein, Xenopus [MeSH Supplementary Concept]
- ARHGEF12 protein, human [MeSH Supplementary Concept]
- ARHGEF17 protein, human [MeSH Supplementary Concept]
- ARHGEF18 protein, human [MeSH Supplementary Concept]
- ARHGEF2 protein, human [MeSH Supplementary Concept]
- ARHGEF25 protein, human [MeSH Supplementary Concept]
- ARHGEF3 protein, human [MeSH Supplementary Concept]
- ARHGEF3 protein, mouse [MeSH Supplementary Concept]
- ARHGEF39 protein, human [MeSH Supplementary Concept]
- ARHGEF4 protein, human [MeSH Supplementary Concept]
- ARHGEF5 protein, human [MeSH Supplementary Concept]
- ARHGEF5 protein, mouse [MeSH Supplementary Concept]
- ARHGEF6 protein, human [MeSH Supplementary Concept]
- ARHGEF7 protein, human [MeSH Supplementary Concept]
- ARHGEF9 protein, human [MeSH Supplementary Concept]
- Arhgef1 protein, mouse [MeSH Supplementary Concept]
- Arhgef12 protein, mouse [MeSH Supplementary Concept]
- Arhgef12 protein, rat [MeSH Supplementary Concept]
- Arhgef15 protein, mouse [MeSH Supplementary Concept]
- Arhgef2 protein, mouse [MeSH Supplementary Concept]
- Arhgef2 protein, rat [MeSH Supplementary Concept]
- Arhgef4 protein, mouse [MeSH Supplementary Concept]
- Arhgef6 protein, mouse [MeSH Supplementary Concept]
- Arhgef7 protein, mouse [MeSH Supplementary Concept]
- Arhgef7 protein, rat [MeSH Supplementary Concept]
- Arhgef9 protein, mouse [MeSH Supplementary Concept]
- Arhgef9 protein, rat [MeSH Supplementary Concept]
- Cep250 protein, mouse [MeSH Supplementary Concept]
- FARP1 protein, human [MeSH Supplementary Concept]
- FARP1 protein, mouse [MeSH Supplementary Concept]
- GEF-H1 protein, Xenopus [MeSH Supplementary Concept]
- GEFT protein, mouse [MeSH Supplementary Concept]
- Gef1 protein, S pombe [MeSH Supplementary Concept]
- Gef3 protein, S pombe [MeSH Supplementary Concept]
- MCF2L protein, human [MeSH Supplementary Concept]
- Mcf2l protein, mouse [MeSH Supplementary Concept]
- OBSCN protein, human [MeSH Supplementary Concept]
- PIX protein, human [MeSH Supplementary Concept]
- PIX protein, rat [MeSH Supplementary Concept]
- PLEKHG1 protein, human [MeSH Supplementary Concept]
- arhgef6 protein, rat [MeSH Supplementary Concept]
- obscn protein, mouse [MeSH Supplementary Concept]
- p63RhoGEF protein, rat [MeSH Supplementary Concept]
- rtGEF protein, drosophila [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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