5-alpha reductase inhibitors

Preferred Label : 5-alpha reductase inhibitors;

MeSH definition : Drugs that inhibit 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE. They are commonly used to reduce the production of DIHYDROTESTOSTERONE.;

MeSH synonym : inhibitors, 5-alpha reductase; reductase inhibitors, 5-alpha; testosterone 5-alpha-Reductase inhibitors; 5-alpha-Reductase inhibitors, testosterone; inhibitors, testosterone 5-alpha-Reductase; testosterone 5 alpha reductase inhibitors; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase inhibitors; 3 oxo 5 alpha steroid 4 dehydrogenase inhibitors; 4-Dehydrogenase inhibitors, 3-Oxo-5-alpha-Steroid; inhibitors, 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; steroid 5-alpha-Reductase inhibitors; 5-alpha-Reductase inhibitors, steroid; inhibitors, steroid 5-alpha-Reductase; steroid 5 alpha reductase inhibitors; 5 alpha reductase inhibitors; Testosterone 5-alpha-Reductase Inhibitor; 5-alpha-Reductase Inhibitor, Testosterone; Inhibitor, Testosterone 5-alpha-Reductase; Testosterone 5 alpha Reductase Inhibitor; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase Inhibitor; 3 Oxo 5 alpha Steroid 4 Dehydrogenase Inhibitor; 4-Dehydrogenase Inhibitor, 3-Oxo-5-alpha-Steroid; Inhibitor, 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Steroid 5-alpha-Reductase Inhibitor; 5-alpha-Reductase Inhibitor, Steroid; Inhibitor, Steroid 5-alpha-Reductase; Steroid 5 alpha Reductase Inhibitor; 5-alpha Reductase Inhibitor; 5 alpha Reductase Inhibitor; Inhibitor, 5-alpha Reductase; Reductase Inhibitor, 5-alpha;

Wikipedia link : https://en.wikipedia.org/wiki/5-alpha reductase inhibitors;

Is substance : O;

action pharmacologique : O;

Details

Origin ID

D058891;

UMLS CUI

C2936788;

ATC code(s)
- testosterone-5-alpha reductase inhibitors [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- 5-alpha reductase inhibitor (disposition) [SNOMED CT concept]
Currated CISMeF NLP mapping
- 5 Alpha-Reductase Inhibitor [NCIt concept]
- 5-alpha-reductase inhibitors [CISMeF Querying Strategy]
- Substance with 5-alpha reductase inhibitor mechanism of action (substance) [SNOMED CT concept]
MeSH Descriptor(s) used for indexing
- 3-Oxo-5-alpha-Steroid 4-Dehydrogenase [MeSH Descriptor]
- cholestenone 5 alpha-reductase [MeSH Descriptor]
Record concept(s)
- 5-alpha reductase inhibitors [MeSH concept]
See also (suggested by CISMeF)
- 3-Oxo-5-alpha-Steroid 4-Dehydrogenase [MeSH Descriptor]
See also inter- (CISMeF)
- Product containing 5-alpha reductase inhibitor (product) [SNOMED CT concept]
Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
Substance(s)
- (22RS-N-1,1,1-trifluoro-2-phenylprop-2-yl)-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxamide [MeSH Supplementary Concept]
- (5alpha)-23-methyl-4-aza-21-norchol-1-ene-3,20-dione [MeSH Supplementary Concept]
- 17 beta-benzoyl-4-aza-5 alpha-androst-1-ene-3-one [MeSH Supplementary Concept]
- 17-(N,N,-diisopropylcarbamoyl)androst-3,5-diene-3-carboxylic acid [MeSH Supplementary Concept]
- 17-(N,N-diisopropylcarbamoyl)estra-1,3,5(10)-triene-3-sulfonic acid [MeSH Supplementary Concept]
- 17-(N,N-diisopropylcarboxamide)estra-1,3,5(10)-triene-3-carboxylic acid [MeSH Supplementary Concept]
- 17-(N-t-butylcarboxamide)estra-1,3,5(10)-triene-3-carboxylic acid [MeSH Supplementary Concept]
- 17-N,N-diethylcarbamoyl-4-methyl-4-azaandrostane-3-one [MeSH Supplementary Concept]
- 17-N,N-diisopropylcarbamoyl-4-azaandrostan-3-one [MeSH Supplementary Concept]
- 17-acetoxy-6-methylene-4-pregnene-3,20-dione [MeSH Supplementary Concept]
- 17-p-bromophenylcarbamoyloxypregn-4-ene-3,20-dione [MeSH Supplementary Concept]
- 17-phenylcarbamoyloxypregn-4-ene-3,20-dione [MeSH Supplementary Concept]
- 2,3,5,6-tetrahydro-4,8-dimethylbenzo(c)quinolizin-3-one [MeSH Supplementary Concept]
- 2-hydroxynonafluoroazobenzene [MeSH Supplementary Concept]
- 20-(hydroxymethyl)-4-methyl-4-aza-2-oxapregnan-3-one [MeSH Supplementary Concept]
- 3'-geranyl-2',3,4,4'-tetrahydroxychalcone [MeSH Supplementary Concept]
- 4,7beta-dimethyl-4-azacholestan-3-one [MeSH Supplementary Concept]
- 4-(3-(3-(bis(4-isobutylphenyl)methylamino)benzoyl)-1H-indol-1-yl)butyric acid [MeSH Supplementary Concept]
- 4-hydroxynonafluoroazobenzene [MeSH Supplementary Concept]
- 4-methoxyandrostenedione [MeSH Supplementary Concept]
- 4-methyl-4-aza-3-oxopregnane-20-carboxylate [MeSH Supplementary Concept]
- 4-methyl-benzo(c)quinolizin-3-one [MeSH Supplementary Concept]
- 6 beta methoxy-9 beta,10 alpha-pregna-4,6-dien-3,20-dione [MeSH Supplementary Concept]
- 8-allyl-7-hydroxy-2H-benzopyran-2-one [MeSH Supplementary Concept]
- 8-chloro-2,3,5,6-tetrahydro-4-methylbenzo(c)quinolizin-3-one [MeSH Supplementary Concept]
- 8-chloro-4-methyl-1,2,3,4,4a,5,6,10b-octahydrobenzo(f)quinolin-3(2H)-one [MeSH Supplementary Concept]
- Ac-AAVALLPAVLLALLAPYVAD-CHO [MeSH Supplementary Concept]
- Dutasteride [MeSH Descriptor]
- FCE 27837 [MeSH Supplementary Concept]
- FCE 28175 [MeSH Supplementary Concept]
- L 685273 [MeSH Supplementary Concept]
- N,N-diethyl-3-oxo-4-azaandrost-1-ene-17-carboxamide [MeSH Supplementary Concept]
- N,N-diethyl-4-methoxy-3-oxo-4-aza-5-androstene-17-carboxamide [MeSH Supplementary Concept]
- N-(1',1'-dimethylethyl)-3-fluoroandrost-3,5-dien-17-carboxamide [MeSH Supplementary Concept]
- N-(1-(4-trifluoromethylphenyl)cyclopentenyl)-3-oxo-4-aza-5a-androst-1-ene-17beta-carboxamide [MeSH Supplementary Concept]
- N-ethyl-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxamide [MeSH Supplementary Concept]
- SNA 4606-1 [MeSH Supplementary Concept]
- WS 9659 B [MeSH Supplementary Concept]
- Z 350 [MeSH Supplementary Concept]
- alfatradiol [MeSH Supplementary Concept]
- azasteroids [MeSH Descriptor]
- epristeride [MeSH Supplementary Concept]
- etienic acid [MeSH Supplementary Concept]
- finasteride [MeSH Descriptor]
- lavanducyanin [MeSH Supplementary Concept]
- testosterone formate [MeSH Supplementary Concept]
- turosteride [MeSH Supplementary Concept]
UMLS correspondences (same concept)
- 5 Alpha-Reductase Inhibitor [NCIt concept]
- 5-alpha-reductase inhibitors [CISMeF Querying Strategy]
- Product containing 5-alpha reductase inhibitor (product) [SNOMED CT concept]
- Substance with 5-alpha reductase inhibitor mechanism of action (substance) [SNOMED CT concept]
Validated automatic mappings to BTNT
- testosterone-5-alpha reductase inhibitors [ATC Code]

Keyword's position in hierarchy(ies) :

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