MeSH definition : A family of secreted proteins found associated with the EXTRACELLULAR MATRIX and cell
surface receptors. They are believed to play a role in modulating the effects of a
variety of GROWTH FACTORS and PROTEASES at the cell membrane extracellular matrix.
The CCN protein family is named after three protypical members; CYSTEINE-RICH PROTEIN
61; CONNECTIVE TISSUE GROWTH FACTOR; and NEPHROBLASTOMA OVEREXPRESSED PROTEIN.;
MeSH synonym : matricellular CCN proteins; CCN family proteins; CYR61 CTGF NOV Matricellular Proteins;
A family of secreted proteins found associated with the EXTRACELLULAR MATRIX and cell
surface receptors. They are believed to play a role in modulating the effects of a
variety of GROWTH FACTORS and PROTEASES at the cell membrane extracellular matrix.
The CCN protein family is named after three protypical members; CYSTEINE-RICH PROTEIN
61; CONNECTIVE TISSUE GROWTH FACTOR; and NEPHROBLASTOMA OVEREXPRESSED PROTEIN.
http://www.john-libbey-eurotext.fr/fr/revues/medecine/bdc/e-docs/00/01/12/D2/resume.phtml?type=text.html 2001 France French CCN intercellular signaling proteins cell growth processes cell differentiation CCN intercellular signaling proteins CCN intercellular signaling proteins gene expression regulation cell proliferation cysteine-rich protein 61 connective tissue growth factor nephroblastoma overexpressed protein journal article