CCN Family Protein

Preferred Label : CCN Family Protein;

NCIt synonyms : CCN; CCN Protein; CCN intercellular Signaling Protein; CCN Family; CYR61/CTGF/NOV Family Protein; CYR61, CTGF, NOV Family Protein; Cellular Communication Network Factor Family;

NCIt definition : A family of dynamically expressed, non-structural, extracellular matrix (ECM)-associated proteins that are involved in a diverse set of cellular signaling pathways. Members of this family are characterized by having four conserved cysteine-rich domains, which includes an N-terminal insulin-like growth factor-binding domain (IGFBP), a von Willebrand factor type C domain (VWFC), a thrombospondin type 1 repeat (TSP type-1), and a C-terminal cysteine knot domain (CTCK).;

NCI Metathesaurus CUI : CL977352;

Details

Origin ID

C164150;

UMLS CUI

C5236014;

Automatic exact mappings (from CISMeF team)
- condensation nuclei [IUPAC Term]
Biochemical function of gene products
- WNT1-Inducible-Signaling Pathway Protein 2 [NCIt concept]
Currated CISMeF NLP mapping
- CCN intercellular signaling proteins [MeSH Descriptor]
- CCN intercellular signaling proteins [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
gene_product_has_biochemical_function
- Insulin-Like Growth Factor-Binding Protein [NCIt concept]
is_chemical_classification_of_gene_product
- CCN Family Member 1 [NCIt concept]
- CCN Family Member 2 [NCIt concept]
- CCN Family Member 3 [NCIt concept]
- Cellular Communication Network Factor 6 [NCIt concept]
- WNT1-Inducible-Signaling Pathway Protein 1 [NCIt concept]

Keyword's position in hierarchy(ies) :

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