Preferred Label : b-cell activating factor;
MeSH definition : A tumor necrosis factor superfamily member that plays a role in the regulation of
B-LYMPHOCYTE survival. It occurs as a membrane-bound protein that is cleaved to release
an biologically active soluble form with specificity to TRANSMEMBRANE ACTIVATOR AND
CAML INTERACTOR PROTEIN; B-CELL ACTIVATION FACTOR RECEPTOR; and B-CELL MATURATION
ANTIGEN.;
MeSH synonym : activating factor, b-cell; b-lymphocyte activating factor; cd257 antigen; cd257 antigens; tall 1 protein; tall-1 protein; tnf and apol-related leukocyte expressed ligand 1; tnf superfamily, member 13b; tumor necrosis factor ligand superfamily member 13b; b lymphocyte activating factor; baff ligand; antigens, cd257; B Lymphocyte Stimulator; activating factor, b-lymphocyte; antigen, cd257; thank protein; tnf and apol related leukocyte expressed ligand 1; blys protein; B cell activating factor; TNFSF13B Protein;
Is substance : O;
Origin ID : D053264;
UMLS CUI : C0767393;
Allowable qualifiers
Automatic exact mappings (from CISMeF team)
Currated CISMeF NLP mapping
Indexing information
Record concept(s)
Related MeSH Supplementary Concept(s)
See also (suggested by CISMeF)
Semantic type(s)
A tumor necrosis factor superfamily member that plays a role in the regulation of
B-LYMPHOCYTE survival. It occurs as a membrane-bound protein that is cleaved to release
an biologically active soluble form with specificity to TRANSMEMBRANE ACTIVATOR AND
CAML INTERACTOR PROTEIN; B-CELL ACTIVATION FACTOR RECEPTOR; and B-CELL MATURATION
ANTIGEN.
http://www.has-sante.fr/portail/jcms/c_1751169/fr/benlysta
http://www.has-sante.fr/portail/jcms/c_1234522/benlysta
2014
false
France
French
evaluation of the transparency committee
antibodies, monoclonal, humanized
antibodies, monoclonal, humanized
guidelines for drug use
secondary prevention
corticosteroid therapy
belimumab
belimumab
antibodies, monoclonal
antibodies, monoclonal
belimumab
immunosuppressive agents
immunosuppressive agents
TNFSF13B protein, human
b-cell activating factor
lupus erythematosus, systemic
treatment outcome
drug therapy, combination
adult
infusions, intravenous
randomized controlled trials as topic
risk management
clinical trials, phase iii as topic
antibodies, antinuclear
Tumor Necrosis Factor Inhibitors
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