Recombinant Interleukin-1

Preferred Label : Recombinant Interleukin-1;

NCIt synonyms : Macrophage Cell Factor; Interleukin 1; Lymphocyte Activating Factor; Lymphocyte-Stimulating Hormone; IL-1; Therapeutic Interleukin-1;

NCIt related terms : Interleukin-1;

NCIt definition : A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine interleukin-1 (IL-1). Produced mainly by monocytes, endogenous IL-1 plays a role in hematopoiesis, is a potent stimulator of T-cell activity, may promote or inhibit tumor growth, depending on tumor type. (NCI04);

NSC code : 618082;

Codes from synonyms : NSC0618082; 31664;

Details

Origin ID

C586;

UMLS CUI

C1522428;

Automatic exact mappings (from CISMeF team)
- b-cell activating factor [MeSH Descriptor]
- caspase 1 [HGNC gene]
- interleukin 37 [HGNC gene]
- interleukin-1 receptor binding [GO term]
Currated CISMeF NLP mapping
- Interleukin 1 [LOINC component]
- Interleukin-1 [FMA entity]
- Interleukin-1 [MeSH Descriptor]
- Interleukin-1 [MeSH concept]
- Interleukin-1 (substance) [SNOMED CT concept]
- interleukin 1 [COVID-19 Thesaurus concept]
- interleukin-1 [SNOMED Notion]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_has_physiologic_effect
- Inhibition of Cell Proliferation [NCIt concept]
is_related_to_endogenous_product
- Interleukin-1 [NCIt concept]

Keyword's position in hierarchy(ies) :

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