complement C1 inhibitor protein

Preferred Label : complement C1 inhibitor protein;

MeSH definition : An endogenous 105-kDa plasma glycoprotein produced primarily by the LIVER and MONOCYTES. It inhibits a broad spectrum of proteases, including the COMPLEMENT C1R and the COMPLEMENT C1S proteases of the CLASSICAL COMPLEMENT PATHWAY, and the MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES. C1-INH-deficient individuals suffer from HEREDITARY ANGIOEDEMA TYPES I AND II.;

MeSH synonym : c1 inh protein; c1-inhibitor protein; c1-inh protein; plasma protease c1 inhibitor; c1 inhibitor protein; Serpin G1; c1 esterase inhibitor; esterase inhibitor, c1; complement C1-Inhibitor protein; Serpin Family G Member 1; SERPING1;

CISMeF synonym : protein, c1-inh; inhibitor, c1 esterase; protein, c1-inhibitor; protein, complement c1-inhibitor; G1, Serpin;

MeSH annotation : do not confuse with COMPLEMENT C1 INACTIVATOR PROTEINS;

Is substance : O;

Details

Origin ID

D050718;

UMLS CUI

C0540301;

ATC code(s)
- C1-inhibitor, plasma derived [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Substance with C1 esterase inhibitor mechanism of action (substance) [SNOMED CT concept]
- c1 complement inhibitor [SNOMED Notion]
Pharmacological action(s)
- complement inactivating agents [MeSH Descriptor]
Record concept(s)
- complement C1 inhibitor protein [MeSH concept]
Related MeSH Supplementary Concept(s)
- SERPING1 protein, human [MeSH Supplementary Concept]
- Serping1 protein, mouse [MeSH Supplementary Concept]
- conestat alfa [MeSH Supplementary Concept]
Related MeSH term(s)
- hereditary angioedema types I and II [MeSH Descriptor]
See also
- hereditary angioedema types I and II [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to BTNT
- Substance with C1q esterase inhibitor mechanism of action (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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