proprotein convertases

Preferred Label : proprotein convertases;

MeSH definition : Proteolytic enzymes that are involved in the conversion of protein precursors such as peptide prohormones into PEPTIDE HORMONES. Some are ENDOPEPTIDASES, some are EXOPEPTIDASES.;

MeSH synonym : convertase, proprotein; convertases, proprotein; proprotein convertase;

DeCS synonym : Proprotein Convertases, Subtilisin-Kexin Family;

MeSH hyponym : Subtilisin-Like proprotein convertases; prohormone convertases; Pro-Opiomelanocortin converting enzyme; Convertases, Prohormone; Prohormone Convertase; Convertase, Prohormone; Proprotein Convertases, Subtilisin Kexin Family; Proprotein Convertase, Subtilisin-Kexin Family; Proprotein Convertase, Subtilisin Kexin Family; Convertases, Subtilisin-Like Proprotein; Proprotein Convertases, Subtilisin-Like; Subtilisin Like Proprotein Convertases; Converting Enzyme, Pro-Opiomelanocortin; Pro Opiomelanocortin Converting Enzyme; POMC Enzyme; POMC-Converting Enzyme; POMC Converting Enzyme; Pro-Opiocortin Converting Protease; Converting Protease, Pro-Opiocortin; Pro Opiocortin Converting Protease; Proopiomelanocortin Convertase; Convertase, Proopiomelanocortin; POMC Convertase; Convertase, POMC; Pro-Opiocortin Converting Enzyme; Converting Enzyme, Pro-Opiocortin; Pro Opiocortin Converting Enzyme;

CISMeF hyponym : EC 3.4.-;

MeSH Related Number : prohormone convertases; Pro-Opiomelanocortin converting enzyme; Subtilisin-Like proprotein convertases; EC 3.4.-; EC 3.4.23.17; EC 3.4.21.-; EC 3.4.21.61;

Registry Number MeSH : EC 3.4.-; EC 3.4.21.-;

Related CAS MeSH : EC 3.4.- (Prohormone convertases); EC 3.4.- (Subtilisin-Like proprotein convertases); EC 3.4.23.17 (Pro-Opiomelanocortin converting enzyme);

Wikipedia link : https://en.wikipedia.org/wiki/Pro-opiomelanocortin converting enzyme;

Is substance : O;

Details

Origin ID

D043484;

UMLS CUI

C1100660;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Pro-opiomelanocortin converting enzyme (substance) [SNOMED CT concept]
Record concept(s)
- Pro-Opiomelanocortin converting enzyme [MeSH concept]
- Proprotein Convertases, Subtilisin-Kexin Family [MeSH concept]
- Subtilisin-Like proprotein convertases [MeSH concept]
- prohormone convertases [MeSH concept]
- proprotein convertases [MeSH concept]
Related MeSH Supplementary Concept(s)
- FurinA protein, zebrafish [MeSH Supplementary Concept]
- KEX2 protein, S cerevisiae [MeSH Supplementary Concept]
- KPC-1 protein, C elegans [MeSH Supplementary Concept]
- PCSK4 protein, human [MeSH Supplementary Concept]
- PCSK6 protein, human [MeSH Supplementary Concept]
- PCSK9 protein, human [MeSH Supplementary Concept]
- Pcsk4 protein, mouse [MeSH Supplementary Concept]
- Pcsk6 protein, mouse [MeSH Supplementary Concept]
- Pcsk6 protein, rat [MeSH Supplementary Concept]
- Pcsk9 protein, mouse [MeSH Supplementary Concept]
- RCE1 protein, S cerevisiae [MeSH Supplementary Concept]
- membrane-bound transcription factor peptidase, site 1 [MeSH Supplementary Concept]
- photosystem II, D1 polypeptide carboxy-terminal processing protease [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

Main resources

You can consult :

recommendations
documents concerning education
documents for patients