Preferred Label : MicroRNAs;
MeSH definition : Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated
from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer,
that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of
the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC)
of target RNA by binding to homologous 3'UTR region as an imperfect match. The small
temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered,
and are from a class of miRNAs involved in developmental timing.;
MeSH synonym : rna, micro; mirnas; mirna; micro rna; microrna;
MeSH hyponym : primary MicroRNA; RNA, small temporal; pre-miRNA; MicroRNA, Primary; Primary miRNA; miRNA, Primary; pri-miRNA; pri miRNA; Temporal RNA, Small; stRNA; Small Temporal RNA; pre miRNA;
Is substance : O;
Origin ID : D035683;
UMLS CUI : C1101610;
Allowable qualifiers
Automatic exact mappings (from CISMeF team)
CISMeF manual mappings
Currated CISMeF NLP mapping
Indexing information
Record concept(s)
Related MeSH Supplementary Concept(s)
See also
Semantic type(s)
UMLS correspondences (same concept)
Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated
from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer,
that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of
the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC)
of target RNA by binding to homologous 3'UTR region as an imperfect match. The small
temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered,
and are from a class of miRNAs involved in developmental timing.
https://www.inserm.fr/actualite/mici-les-microarn-dans-le-viseur/
2025
France
popular works
MicroRNAs
inflammatory bowel diseases
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https://www.jle.com/fr/revues/bio_rech/vir/e-docs/00/04/8F/AA/resume.phtml
10.1684/vir.2013.0538
2013
false
true
false
France
journal article
MicroRNAs
host-pathogen interactions
gene expression regulation
MicroRNAs
viruses
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