Preferred Label : MicroRNAs;
MeSH definition : Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated
from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer,
that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of
the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC)
of target RNA by binding to homologous 3'UTR region as an imperfect match. The small
temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered,
and are from a class of miRNAs involved in developmental timing.;
MeSH synonym : rna, micro; mirnas; mirna; micro rna; microrna;
MeSH hyponym : primary MicroRNA; RNA, small temporal; pre-miRNA; MicroRNA, Primary; Primary miRNA; miRNA, Primary; pri-miRNA; pri miRNA; Temporal RNA, Small; stRNA; Small Temporal RNA; pre miRNA;
Is substance : O;
Origin ID : D035683;
UMLS CUI : C1101610;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- CISMeF manual mappings
- Currated CISMeF NLP mapping
- Indexing information
- Record concept(s)
- Related MeSH Supplementary Concept(s)
- See also
- Semantic type(s)
- UMLS correspondences (same concept)
Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated
from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer,
that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of
the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC)
of target RNA by binding to homologous 3'UTR region as an imperfect match. The small
temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered,
and are from a class of miRNAs involved in developmental timing.
https://www.jle.com/fr/revues/bio_rech/vir/e-docs/00/04/8F/AA/resume.phtml
10.1684/vir.2013.0538
2013
false
true
false
France
journal article
MicroRNAs
host-pathogen interactions
gene expression regulation
MicroRNAs
viruses
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