epothilones - CISMeF

Preferred Label : epothilones;

MeSH definition : A group of 16-member MACROLIDES which stabilize MICROTUBULES in a manner similar to PACLITAXEL. They were originally found in the myxobacterium Sorangium cellulosum, now renamed to Polyangium (MYXOCOCCALES).;

MeSH synonym : epothilon; epothilone;

Wikipedia link : https://en.wikipedia.org/wiki/Epothilone;

Is substance : O;

Details

Origin ID

D034261;

UMLS CUI

C1136012;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Epothilone (substance) [SNOMED CT concept]
- Epothilone A [NCIt concept]
- Epothilone Compound [NCIt concept]
Indexing information
- epothilone C-D monooxygenase [MeSH Supplementary Concept]
Pharmacological action(s)
- tubulin modulators [MeSH Descriptor]
Record concept(s)
- epothilones [MeSH concept]
Related MeSH Supplementary Concept(s)
- (S)-14-methoxyepothilone [MeSH Supplementary Concept]
- 10,11-didehydroepothilone D [MeSH Supplementary Concept]
- 10,14-dihydroxy-9,11,13,13-tetramethyl-2-(1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl)-5-(7-nitro-benzo(1,2,5)oxadiazol-4-yl)-1-oxa-5-aza-cyclohexadecane-12,16-dione [MeSH Supplementary Concept]
- 12,13-cyclopropyl-epothilone B [MeSH Supplementary Concept]
- 12,13-desoxyepothilone F [MeSH Supplementary Concept]
- 15-aza-12,13-desoxyepothilone B [MeSH Supplementary Concept]
- 26-trifluoro-(E)-9,10-dehydro-12,13-desoxyepothilone B [MeSH Supplementary Concept]
- 9,10-dehydroepothilone D [MeSH Supplementary Concept]
- AV-EPO-106 [MeSH Supplementary Concept]
- BMS 310705 [MeSH Supplementary Concept]
- BMS-748285 [MeSH Supplementary Concept]
- BMS-753493 [MeSH Supplementary Concept]
- C12,13-cyclopropylepothilone A [MeSH Supplementary Concept]
- C26-hydroxyepothilone D [MeSH Supplementary Concept]
- KOS-1584 [MeSH Supplementary Concept]
- cryptothilone 1 [MeSH Supplementary Concept]
- desoxyepothilone A [MeSH Supplementary Concept]
- desoxyepothilone B [MeSH Supplementary Concept]
- epothilone 490 [MeSH Supplementary Concept]
- epothilone A [MeSH Supplementary Concept]
- epothilone B [MeSH Supplementary Concept]
- epothilone C [MeSH Supplementary Concept]
- epothilone E [MeSH Supplementary Concept]
- epothilone F [MeSH Supplementary Concept]
- epothilone I [MeSH Supplementary Concept]
- epothilone K [MeSH Supplementary Concept]
- fludelone [MeSH Supplementary Concept]
- ixabepilone [MeSH Supplementary Concept]
- sagopilone [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Ixabepilone [NCIt concept]
- Ixabepilone (substance) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Epothilone (substance) [SNOMED CT concept]
- Epothilone Compound [NCIt concept]

Keyword's position in hierarchy(ies) :

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