Epothilone Compound

Preferred Label : Epothilone Compound;

NCIt related terms : epothilone;

NCIt definition : A class of compounds isolated from the myxobacterium Sorangium cellulosum. Similar to taxanes, epothilone compounds induce microtubule polymerization and stabilize microtubules against depolymerization conditions, thereby inhibiting mitosis. (NCI);

Alternative definition : NCI-GLOSS: A substance obtained from bacteria that interferes with cell division. Some epothilones are being studied as treatments for cancer.;

ChEBI ID : CHEBI:60831;

Codes from synonyms : CDR0000269418;

Details

Origin ID

C1922;

UMLS CUI

C1136012;

Automatic exact mappings (from CISMeF team)
- Epothilone (substance) [SNOMED CT concept]
- epothilone A [MeSH concept]
- epothilone A [MeSH Supplementary Concept]
- epothilones [MeSH concept]
- epothilones [MeSH Descriptor]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Epothilone (substance) [SNOMED CT concept]
- epothilones [MeSH concept]
- epothilones [MeSH Descriptor]
chemical_or_drug_plays_role_in_biological_process
- Negative Regulation of Microtubule Depolymerization [NCIt concept]

Keyword's position in hierarchy(ies) :

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