Mitogen-Activated protein kinases

Preferred Label : Mitogen-Activated protein kinases;

MeSH definition : A superfamily of PROTEIN-SERINE-THREONINE KINASES that are activated by diverse stimuli via protein kinase cascades. They are the final components of the cascades, activated by phosphorylation by MITOGEN-ACTIVATED PROTEIN KINASE KINASES, which in turn are activated by mitogen-activated protein kinase kinase kinases (MAP KINASE KINASE KINASES).; A superfamily of PROTEIN SERINE-THREONINE KINASES that are activated by diverse stimuli via protein kinase cascades. They are the final components of the cascades, activated by phosphorylation by MITOGEN-ACTIVATED PROTEIN KINASE KINASES, which in turn are activated by mitogen-activated protein kinase kinase kinases (MAP KINASE KINASE KINASES).;

MeSH synonym : kinases, mitogen-activated protein; protein kinases, mitogen-activated; mitogen activated protein kinases; Mitogen Activated Protein Kinase; Mitogen-Activated Protein Kinase; Kinase, Mitogen-Activated Protein; Protein Kinase, Mitogen-Activated;

CISMeF synonym : EC 2.7.1.37;

Registry Number MeSH : EC 2.7.11.24;

Wikipedia link : https://en.wikipedia.org/wiki/Mitogen-activated protein kinases;

Is substance : O;

UNII : EC 2.7.11.24;

Details

Origin ID

D020928;

UMLS CUI

C0752312;

ATC code(s)
- Mitogen-activated protein kinase (MEK) inhibitors [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- MAP Kinase Gene [NCIt concept]
- MUTYH-Associated Polyposis [NCIt concept]
- Potassium-aggravated myotonia [ORDO Disease]
- Serine/Threonine-Protein Kinase NLK [NCIt concept]
- Threatened premature delivery [PASCAL descriptor]
- threatened premature labor [SNOMED Notion]
Currated CISMeF NLP mapping
- Mitogen-Activated Protein Kinase [NCIt concept]
- Mitogen-Activated Protein Kinases [LOINC hierarchical part]
Indexing information
- NLK protein, human [MeSH Supplementary Concept]
- NLK protein, rat [MeSH Supplementary Concept]
- RWJ 67657 [MeSH Supplementary Concept]
- unc-16 protein, C elegans [MeSH Supplementary Concept]
Record concept(s)
- Mitogen-Activated protein kinases [MeSH concept]
Related MeSH Supplementary Concept(s)
- ATMPK1 protein, arabidopsis [MeSH Supplementary Concept]
- AtMPK4 protein, arabidopsis [MeSH Supplementary Concept]
- Chk1 protein, cochliobolus [MeSH Supplementary Concept]
- DYF-5 protein, C elegans [MeSH Supplementary Concept]
- FUS3 protein, S cerevisiae [MeSH Supplementary Concept]
- Fmk1 protein, fusarium oxysporum [MeSH Supplementary Concept]
- HOG1 protein, S cerevisiae [MeSH Supplementary Concept]
- JNK-1 protein, C elegans [MeSH Supplementary Concept]
- KSS1 protein, S cerevisiae [MeSH Supplementary Concept]
- MK1 protein, capsicum annuum [MeSH Supplementary Concept]
- MKC1 protein, candida albicans [MeSH Supplementary Concept]
- MKK3 protein, Arabidopsis [MeSH Supplementary Concept]
- MKK9 protein, arabidopsis [MeSH Supplementary Concept]
- MKP1 protein, arabidopsis [MeSH Supplementary Concept]
- MMK1 protein, medicago sativa [MeSH Supplementary Concept]
- MMK2 protein, medicago sativa [MeSH Supplementary Concept]
- MMK4 protein, Medicago sativa [MeSH Supplementary Concept]
- MOK protein, human [MeSH Supplementary Concept]
- MPK11 protein, arabidopsis [MeSH Supplementary Concept]
- MPK12 protein, Oryza sativa [MeSH Supplementary Concept]
- MPK12 protein, arabidopsis [MeSH Supplementary Concept]
- MPK17 protein, Arabidopsis [MeSH Supplementary Concept]
- MPK2 protein, arabidopsis [MeSH Supplementary Concept]
- MPK6 protein, arabidopsis [MeSH Supplementary Concept]
- MPK8 protein, arabidopsis [MeSH Supplementary Concept]
- MPK9 protein, arabidopsis [MeSH Supplementary Concept]
- Map2k7 protein, rat [MeSH Supplementary Concept]
- Mok protein, mouse [MeSH Supplementary Concept]
- NTF3 protein, nicotiana tabacum [MeSH Supplementary Concept]
- PK6 protein, plasmodium falciparum [MeSH Supplementary Concept]
- Pim1 protein, Pichia pastoris [MeSH Supplementary Concept]
- Pmk-1 protein, C elegans [MeSH Supplementary Concept]
- Pmk1 protein, S pombe [MeSH Supplementary Concept]
- Pmk1 protein, magnaporthe grisea [MeSH Supplementary Concept]
- Ptk1 protein, pyrenophora teres [MeSH Supplementary Concept]
- RISK-1 kinase, Aplysia [MeSH Supplementary Concept]
- SA-induced protein kinase [MeSH Supplementary Concept]
- SLT2 protein, S cerevisiae [MeSH Supplementary Concept]
- SRK1 protein, S pombe [MeSH Supplementary Concept]
- Smk1 protein, S cerevisiae [MeSH Supplementary Concept]
- Spc1 protein, S pombe [MeSH Supplementary Concept]
- Spk1 protein, S pombe [MeSH Supplementary Concept]
- TVK1 protein, trichoderma virens [MeSH Supplementary Concept]
- WCK-1 protein, triticum aestivum [MeSH Supplementary Concept]
- WIPK protein, nicotiana tabacum [MeSH Supplementary Concept]
- ZmMPK5 [MeSH Supplementary Concept]
- cmk1 protein, colletotrichum lagenarium [MeSH Supplementary Concept]
- kpp2 protein, ustilago maydis [MeSH Supplementary Concept]
- map-2 protein, plasmodium falciparum [MeSH Supplementary Concept]
- mapk14a protein, xenopus [MeSH Supplementary Concept]
- mitogen-activated protein kinase 11, mouse [MeSH Supplementary Concept]
- nemo like kinase, xenopus [MeSH Supplementary Concept]
- nemo-like kinase, zebrafish [MeSH Supplementary Concept]
- nlk protein, mouse [MeSH Supplementary Concept]
- nmo protein, Drosophila [MeSH Supplementary Concept]
- os-2 protein, neurospora crassa [MeSH Supplementary Concept]
- p43Ntf6MAP kinase, nicotiana tabacum [MeSH Supplementary Concept]
- pmk-2 protein, C elegans [MeSH Supplementary Concept]
- pmk-3 protein, C elegans [MeSH Supplementary Concept]
- salt stress-induced MAP kinase [MeSH Supplementary Concept]
- sek-3 protein, C elegans [MeSH Supplementary Concept]
- sty1 protein, S pombe [MeSH Supplementary Concept]
- ubc2 protein, ustilago maydis [MeSH Supplementary Concept]
See also
- map kinase signaling system [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Mitogen-Activated Protein Kinase [NCIt concept]
- Mitogen-Activated Protein Kinases [LOINC hierarchical part]

Keyword's position in hierarchy(ies) :

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