kininogen, high-molecular-weight

Preferred Label : kininogen, high-molecular-weight;

MeSH definition : A plasma protein, molecular weight of 110 kD, that normally exists in plasma in a 1:1 complex with PREKALLIKREIN. HMWK is split by plasma kallikrein to produce BRADYKININ. The complex is a cofactor in the activation of coagulation factor XII. The product of this reaction, XIIa, in turn activates prekallikrein to KALLIKREINS. (From Stedman, 26th ed);

MeSH synonym : high-molecular-weight kininogens; high-molecular-weight kininogen; high molecular weight kininogen; high molecular weight kininogens; kininogens, high molecular weight; hmwk; kininogens, high-molecular-weight; fitzgerald factor; kininogen, high molecular weight;

MeSH annotation : DF: HMWK;

Wikipedia link : https://en.wikipedia.org/wiki/Kininogen, high-molecular-weight;

Is substance : O;

Details

Origin ID

D019679;

UMLS CUI

C0019536;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- High molecular weight kininogen (substance) [SNOMED CT concept]
- Kininogen HMW [LOINC component]
- Kininogen-1 [NCIt concept]
- high molecular weight kininogen [SNOMED Notion]
Record concept(s)
- kininogen, High-Molecular-Weight [MeSH concept]
Related MeSH Supplementary Concept(s)
- HKa protein, human [MeSH Supplementary Concept]
- flaujeac factor deficiency [MeSH Supplementary Concept]
See also (suggested by CISMeF)
- flaujeac factor deficiency [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- High molecular weight kininogen (substance) [SNOMED CT concept]
- Kininogen HMW [LOINC component]
- high molecular weight kininogen [SNOMED Notion]

Keyword's position in hierarchy(ies) :

Main resources

You can consult :

recommendations
documents concerning education
documents for patients