cystic fibrosis transmembrane conductance regulator

Preferred Label : cystic fibrosis transmembrane conductance regulator;

MeSH definition : A chloride channel that regulates secretion in many exocrine tissues. Abnormalities in the CFTR gene have been shown to cause cystic fibrosis. (Hum Genet 1994;93(4):364-8);

MeSH synonym : cftr protein; protein, cftr; Chloride channels, ATP-gated CFTR; Chloride channels, ATP gated CFTR;

Registry Number MeSH : 126880-72-6;

MeSH annotation : a chloride channel; DF: note short X ref;

Is substance : O;

Details

Origin ID

D019005;

UMLS CUI

C0056889;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Indexing information
- Gpact-11a compound [MeSH Supplementary Concept]
- YCF1 protein, S cerevisiae [MeSH Supplementary Concept]
- ivacaftor [MeSH Supplementary Concept]
- lumacaftor [MeSH Supplementary Concept]
Record concept(s)
- cystic fibrosis transmembrane conductance regulator [MeSH concept]
Related MeSH Supplementary Concept(s)
- CFTR protein, human [MeSH Supplementary Concept]
- CFTR protein, rat [MeSH Supplementary Concept]
- CFTR protein, zebrafish [MeSH Supplementary Concept]
- Cftr protein, mouse [MeSH Supplementary Concept]
- FtsE protein, E coli [MeSH Supplementary Concept]
- cystic fibrosis transmembrane conductance regulator (505-511) [MeSH Supplementary Concept]
- cystic fibrosis transmembrane conductance regulator delta F508 [MeSH Supplementary Concept]
See also
- cystic fibrosis [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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