Cyclin-Dependent kinases

Preferred Label : Cyclin-Dependent kinases;

Obsolete resource : false;

MeSH definition : Protein kinases that control cell cycle progression in all eukaryotes and require physical association with CYCLINS to achieve full enzymatic activity. Cyclin-dependent kinases are regulated by phosphorylation and dephosphorylation events.;

MeSH synonym : cyclin-dependent protein kinases; cyclin dependent protein kinases; cdk proteins; cyclin dependent kinases; Cyclin-Dependent Protein Kinase; Cyclin Dependent Protein Kinase; Kinase, Cyclin-Dependent Protein; Protein Kinase, Cyclin-Dependent; Cyclin-Dependent Kinase; Cyclin Dependent Kinase; Kinase, Cyclin-Dependent;

CISMeF synonym : EC 2.7.1.37;

Registry Number MeSH : EC 2.7.11.22;

Wikipedia link : https://en.wikipedia.org/wiki/Cyclin-dependent kinase;

Is substance : O;

UNII : EC 2.7.11.22;

Details

Origin ID

D018844;

UMLS CUI

C0243045;

ATC code(s)
- Cyclin-dependent kinase (CDK) inhibitors [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Cyclin-Dependent Kinase 7 [NCIt concept]
- Cyclin-Dependent Kinase 8 [NCIt concept]
Currated CISMeF NLP mapping
- Cyclin-Dependent Kinase [NCIt concept]
Indexing information
- 14-methyl-20-oxa-5,7,14,26-tetraazatetracyclo(19.3.1.1(2,6).1(8,12))heptacosa-1(25),2(26),3,5,8(27),9,11,16,21,23-decaene [MeSH Supplementary Concept]
- 2-(2-(hydroxymethyl)pyrrolidinyl)-6-((3-iodophenyl)methylamino)-9-isopropylpurine [MeSH Supplementary Concept]
- 2-(2-chlorophenyl)-5,7-dihydroxy-8-(2,3,6-trihydro-1-methylpyridin-4-yl)benzopyran-4-one [MeSH Supplementary Concept]
- 2-(4-((6,7-dihydro-7-oxo-5H-thiazolo(5,4-e)indol-8-ylidene)amino)phenylsulfamido)pyridine [MeSH Supplementary Concept]
- 3-(4-methoxyphenyl)-5-(morpholinylcarbamoyl)aminoindeno(1,2-c)pyrazol-4-one [MeSH Supplementary Concept]
- 4-(2,6-dichlorobenzoylamino)-1H-pyrazole-3-carboxylic acid piperidin-4-ylamide [MeSH Supplementary Concept]
- 7-benzylamino-5-(2-(hydroxymethyl)propyl)amino-3-isopropyl-1(2)H-pyrazolo(4,3-d)pyrimidine [MeSH Supplementary Concept]
- AG-012986 [MeSH Supplementary Concept]
- AZD5438 [MeSH Supplementary Concept]
- CDK2AP1 protein, human [MeSH Supplementary Concept]
- CR8 compound [MeSH Supplementary Concept]
- CeReS-18 protein, bos taurus [MeSH Supplementary Concept]
- H717 compound [MeSH Supplementary Concept]
- ICK2 protein, arabidopsis [MeSH Supplementary Concept]
- L 868276 [MeSH Supplementary Concept]
- N(2)-(2-aminocyclohexyl)-N(6)-(3-chlorophenyl)-9-ethyl-9H-purine-2,6-diamine [MeSH Supplementary Concept]
- N-(6,6-dimethyl-5-((1-methylpiperidin-4-yl)carbonyl)-1,4,5,6-tetrahydropyrrolo(3,4-c)pyrazol-3-yl)-3-methylbutanamide [MeSH Supplementary Concept]
- N2-(4-aminocyclohexyl)-9-cyclopentyl-N6-(6-(2-hydroxyphenyl)pyridin-3-ylmethyl)-9H-purine-2,6-diamine [MeSH Supplementary Concept]
- PD 0183812 [MeSH Supplementary Concept]
- PHO81 protein, S cerevisiae [MeSH Supplementary Concept]
- Roscovitine [MeSH Descriptor]
- Rum1 protein, S pombe [MeSH Supplementary Concept]
- S-CR8 compound [MeSH Supplementary Concept]
- VER 54505 [MeSH Supplementary Concept]
- alvocidib [MeSH Supplementary Concept]
- dap protein, Drosophila [MeSH Supplementary Concept]
- dinaciclib [MeSH Supplementary Concept]
- indirubin-5-sulfonic acid [MeSH Supplementary Concept]
- kenpaullone [MeSH Supplementary Concept]
- olomoucine [MeSH Supplementary Concept]
- olomoucine II [MeSH Supplementary Concept]
- palbociclib [MeSH Supplementary Concept]
Record concept(s)
- Cyclin-Dependent kinases [MeSH concept]
Related MeSH Supplementary Concept(s)
- CDK1 protein, human [MeSH Supplementary Concept]
- CDK10 protein, human [MeSH Supplementary Concept]
- CDK10 protein, zebrafish [MeSH Supplementary Concept]
- CDK11B protein, human [MeSH Supplementary Concept]
- CDK11a protein, human [MeSH Supplementary Concept]
- CDK12 protein, human [MeSH Supplementary Concept]
- CDK12 protein, mouse [MeSH Supplementary Concept]
- CDK12 protein, rat [MeSH Supplementary Concept]
- CDK14 protein, human [MeSH Supplementary Concept]
- CDK15 protein, human [MeSH Supplementary Concept]
- CDK19 protein, human [MeSH Supplementary Concept]
- CDK19 protein, mouse [MeSH Supplementary Concept]
- CDKA1 protein, arabidopsis [MeSH Supplementary Concept]
- CDKB1 protein, lycopersicon esculentum [MeSH Supplementary Concept]
- CDKB1;2 protein, arabidopsis [MeSH Supplementary Concept]
- CDKB2;1 protein, arabidopsis [MeSH Supplementary Concept]
- CDKC protein, Solanum lycopersicum [MeSH Supplementary Concept]
- CDKC;1 protein, arabidopsis [MeSH Supplementary Concept]
- CDKC;2 protein, arabidopsis [MeSH Supplementary Concept]
- CDKD;2 protein, arabidopsis [MeSH Supplementary Concept]
- CDKD;3 protein, Arabidopsis [MeSH Supplementary Concept]
- CDKG1 protein, Arabidopsis [MeSH Supplementary Concept]
- CDKL-1 protein, C elegans [MeSH Supplementary Concept]
- CDKL1 protein, human [MeSH Supplementary Concept]
- CDKL2 protein, human [MeSH Supplementary Concept]
- CDKb2;2 protein, arabidopsis [MeSH Supplementary Concept]
- CRK6 protein, Arabidopsis [MeSH Supplementary Concept]
- CRK7 protein, Arabidopsis [MeSH Supplementary Concept]
- Cdk1 protein, rat [MeSH Supplementary Concept]
- Cdk10 protein, mouse [MeSH Supplementary Concept]
- Cdk14 protein, rat [MeSH Supplementary Concept]
- CdkB1 protein, nicotiana tabacum [MeSH Supplementary Concept]
- Cdkl2 protein, mouse [MeSH Supplementary Concept]
- Cdkl3 protein, rat [MeSH Supplementary Concept]
- Cks30A protein, drosophila [MeSH Supplementary Concept]
- Cks85A protein, drosophila [MeSH Supplementary Concept]
- Cyclin-dependent kinase 11p110, human [MeSH Supplementary Concept]
- Eip63E protein, drosophila [MeSH Supplementary Concept]
- GIN4 protein, S cerevisiae [MeSH Supplementary Concept]
- Kin28 protein kinase, S cerevisiae [MeSH Supplementary Concept]
- Lsk1 protein, S pombe [MeSH Supplementary Concept]
- PCTAIRE-1 protein kinase [MeSH Supplementary Concept]
- PCTAIRE-2 protein kinase [MeSH Supplementary Concept]
- PCTAIRE-3 protein kinase [MeSH Supplementary Concept]
- PHO85 protein, S cerevisiae [MeSH Supplementary Concept]
- PK6 protein, plasmodium falciparum [MeSH Supplementary Concept]
- PSTAIRE p34 protein, fucus [MeSH Supplementary Concept]
- SGV1 protein, S cerevisiae [MeSH Supplementary Concept]
- TBPK50 protein, trypanosoma brucei [MeSH Supplementary Concept]
- TPK2 protein, toxoplasma gondii [MeSH Supplementary Concept]
- cdkB2 protein, Solanum lycopersicum [MeSH Supplementary Concept]
- cyclin-dependent kinase 7, mouse [MeSH Supplementary Concept]
- cyclin-dependent kinase E1, arabidopsis [MeSH Supplementary Concept]
- p9(Cks1) protein, human [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Cyclin-Dependent Kinase Gene [NCIt concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Cyclin-Dependent Kinase [NCIt concept]

Keyword's position in hierarchy(ies) :

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