Preferred Label : sarcoma, clear cell;
MeSH definition : A sarcoma of young, often female, adults of the lower extremities and acral regions,
intimately bound to tendons as circumscribed but unencapsulated melanin-bearing tumors
of neuroectodermal origin. An ultrastructural finding simulates flattened and curved
barrel staves, corresponding to the internal structures of premelanosomes. There is
a 45-60% mortality in clear cell sarcoma. (Segen, Dictionary of Modern Medicine, 1992); A sarcoma of young adults occurring in the lower extremities and acral regions. It
is found intimately bound to tendons as a circumscribed but unencapsulated melanin-bearing
tumor of neuroectodermal origin. Clear cell sarcoma is associated with a specific
t(12;22)(q13;q12) translocation.;
MeSH synonym : clear cell sarcoma; clear cell sarcomas; sarcomas, clear cell; melanoma, malignant, of soft parts; Clear Cell Sarcoma of Soft Tissue; Malignant Melanoma of Soft Parts; Melanoma of Soft Parts;
MeSH annotation : /blood supply /chem /second /secret /ultrastruct permitted; coord IM with precoord
organ/neopl term (IM); coordinate with precoordinated organ/neoplasm term;
Wikipedia link : https://en.wikipedia.org/wiki/Clear cell sarcoma;
Origin ID : D018227;
UMLS CUI : C0206651;
Allowable qualifiers
Automatic exact mappings (from CISMeF team)
Currated CISMeF NLP mapping
DO Cross reference
Record concept(s)
Semantic type(s)
UMLS correspondences (same concept)
A sarcoma of young, often female, adults of the lower extremities and acral regions,
intimately bound to tendons as circumscribed but unencapsulated melanin-bearing tumors
of neuroectodermal origin. An ultrastructural finding simulates flattened and curved
barrel staves, corresponding to the internal structures of premelanosomes. There is
a 45-60% mortality in clear cell sarcoma. (Segen, Dictionary of Modern Medicine, 1992)
A sarcoma of young adults occurring in the lower extremities and acral regions. It
is found intimately bound to tendons as a circumscribed but unencapsulated melanin-bearing
tumor of neuroectodermal origin. Clear cell sarcoma is associated with a specific
t(12;22)(q13;q12) translocation.
http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=FR&Expert=97338
2011
France
scientific and technical information
tendons
sarcoma, clear cell
melanoma
---
https://www.jle.com/fr/revues/medecine/bdc/e-docs/00/04/4F/56/resume.phtml?type=text.html
2009
France
French
journal article
practice guideline
soft tissue neoplasms
sarcoma
sarcoma, clear cell
soft tissue neoplasms
sarcoma
antineoplastic agents, alkylating
dioxoles
tetrahydroisoquinolines
Trabectedin
---