Preferred Label : sarcoma, clear cell;

MeSH definition : A sarcoma of young, often female, adults of the lower extremities and acral regions, intimately bound to tendons as circumscribed but unencapsulated melanin-bearing tumors of neuroectodermal origin. An ultrastructural finding simulates flattened and curved barrel staves, corresponding to the internal structures of premelanosomes. There is a 45-60% mortality in clear cell sarcoma. (Segen, Dictionary of Modern Medicine, 1992); A sarcoma of young adults occurring in the lower extremities and acral regions. It is found intimately bound to tendons as a circumscribed but unencapsulated melanin-bearing tumor of neuroectodermal origin. Clear cell sarcoma is associated with a specific t(12;22)(q13;q12) translocation.;

MeSH synonym : clear cell sarcoma; clear cell sarcomas; sarcomas, clear cell; melanoma, malignant, of soft parts; Clear Cell Sarcoma of Soft Tissue; Malignant Melanoma of Soft Parts; Melanoma of Soft Parts;

MeSH annotation : /blood supply /chem /second /secret /ultrastruct permitted; coord IM with precoord organ/neopl term (IM); coordinate with precoordinated organ/neoplasm term;

Wikipedia link : https://en.wikipedia.org/wiki/Clear cell sarcoma;

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A sarcoma of young, often female, adults of the lower extremities and acral regions, intimately bound to tendons as circumscribed but unencapsulated melanin-bearing tumors of neuroectodermal origin. An ultrastructural finding simulates flattened and curved barrel staves, corresponding to the internal structures of premelanosomes. There is a 45-60% mortality in clear cell sarcoma. (Segen, Dictionary of Modern Medicine, 1992)
A sarcoma of young adults occurring in the lower extremities and acral regions. It is found intimately bound to tendons as a circumscribed but unencapsulated melanin-bearing tumor of neuroectodermal origin. Clear cell sarcoma is associated with a specific t(12;22)(q13;q12) translocation.

http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=FR&Expert=97338
2011
France
scientific and technical information
tendons
sarcoma, clear cell
melanoma

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https://www.jle.com/fr/revues/medecine/bdc/e-docs/00/04/4F/56/resume.phtml?type=text.html
2009
France
French
journal article
practice guideline
soft tissue neoplasms
sarcoma
sarcoma, clear cell
soft tissue neoplasms
sarcoma
antineoplastic agents, alkylating
dioxoles
tetrahydroisoquinolines
Trabectedin

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14/05/2024


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