Preferred Label : kleine-levin syndrome;
MeSH definition : A rare condition characterized by recurrent hypersomnias associated with hyperphagia,
occurring primarily in males in the second to third decade of life. Clinical features
include mental confusion, excessive sleep requirements (approximately 18 hours per
day), restlessness, and in some cases hallucinations. Episodes have a duration of
days to weeks, and may recur several times per year. This condition may resolve spontaneously
over several years. (From Adams, et al., Principles of Neurology, 6th ed, p569);
MeSH synonym : syndrome, kleine-levin-critchley; kleine-levin-critchley syndrome; syndrome, kleine-levin; hypersomnia, periodic; periodic hypersomnia; periodic hypersomnias; kleine levin critchley syndrome; Kleine-Levin hibernation syndrome; hibernation syndrome, Kleine-Levin; kleine levin hibernation syndrome; syndrome, Kleine-Levin hibernation; kleine levin syndrome;
CISMeF synonym : Kleine-Levin; KLS; kleine-levin's syndrome;
Related MeSH term : familial Kleine-Levin syndrome; Familial Kleine Levin Syndrome; Kleine-Levin Syndrome, Familial; Syndrome, Familial Kleine-Levin; Familial Hibernation (Kleine-Levin) Syndrome;
Wikipedia link : https://en.wikipedia.org/wiki/Kleine-levin syndrome;
Origin ID : D017593;
UMLS CUI : C0206085;
Allowable qualifiers
Automatic exact mappings (from CISMeF team)
Currated CISMeF NLP mapping
DO Cross reference
ORDO relation(s)
Record concept(s)
Semantic type(s)
UMLS correspondences (same concept)
A rare condition characterized by recurrent hypersomnias associated with hyperphagia,
occurring primarily in males in the second to third decade of life. Clinical features
include mental confusion, excessive sleep requirements (approximately 18 hours per
day), restlessness, and in some cases hallucinations. Episodes have a duration of
days to weeks, and may recur several times per year. This condition may resolve spontaneously
over several years. (From Adams, et al., Principles of Neurology, 6th ed, p569)
https://www.has-sante.fr/jcms/p_3292295/fr/syndrome-kleine-levin
2021
false
false
false
France
case management
kleine-levin syndrome
kleine-levin syndrome
hydroxyzine
risperidone
Aripiprazole
acetazolamide
methylprednisolone
methylprednisolone
lithium
lithium
lithium
practice guideline
kleine-levin syndrome
---
http://www.kls-france.org/
France
French
kleine-levin syndrome
association of patients
---
http://www.cochrane.org/fr/CD006685
2013
United Kingdom
France
French
meta-analysis
treatment outcome
kleine-levin syndrome
french abstract
---
http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=FR&Expert=33543
http://www.orpha.net/data/patho/Pro/fr/KleineLevin-FRfrPro10326.pdf
2008
France
French
signs and symptoms
kleine-levin syndrome
kleine-levin syndrome
scientific and technical information
practice guideline
---