ICD-11 code : 7A22;
Preferred Label : Kleine-Levin syndrome;
ICD-11 definition : Kleine-Levin syndrome is characterised by recurrent episodes of severe sleepiness
in association with cognitive, psychiatric, and behavioural disturbances. A typical
episode lasts a median of 10 days (range 2.5–80 days), with rare episodes lasting
several weeks to months. During episodes, patients may sleep as long as 16 to 20 hours
per day, waking or getting up only to eat and void. When awake during episodes, most
patients are exhausted, apathetic, confused, and slow in speaking and answering. Hyperphagia,
hypersexuality, childish behaviour, depression, anxiety, hallucinations and delusions
are often observed during the episodes. Patients are normal between episodes with
regard to sleep, cognition, mood, and eating. Rarely, Kleine Levin syndrome may occur
exclusively during menstrual periods.;
ICD-11 synonym : hypersomnia-bulimia syndrome; recurrent hypersomnolence;
ICD-11 inclusion : recurrent hypersomnolence;
Origin ID : 1180849398;
Currated CISMeF NLP mapping
- ICD-10 Mapping
Kleine-Levin syndrome is characterised by recurrent episodes of severe sleepiness
in association with cognitive, psychiatric, and behavioural disturbances. A typical
episode lasts a median of 10 days (range 2.5–80 days), with rare episodes lasting
several weeks to months. During episodes, patients may sleep as long as 16 to 20 hours
per day, waking or getting up only to eat and void. When awake during episodes, most
patients are exhausted, apathetic, confused, and slow in speaking and answering. Hyperphagia,
hypersexuality, childish behaviour, depression, anxiety, hallucinations and delusions
are often observed during the episodes. Patients are normal between episodes with
regard to sleep, cognition, mood, and eating. Rarely, Kleine Levin syndrome may occur
exclusively during menstrual periods.
