plasminogen activator inhibitor 1

Preferred Label : plasminogen activator inhibitor 1;

MeSH definition : A member of the serpin family of proteins. It inhibits both the tissue-type and urokinase-type plasminogen activators.;

MeSH synonym : type 1 plasminogen activator inhibitor; pai-1; Serpin E1; E1, Serpin; SERPINE1 Protein; Protein, SERPINE1;

Is substance : O;

Details

Origin ID

D017395;

UMLS CUI

C0030190;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Plasminogen Activator Inhibitor-1 Antigen Measurement [NCIt concept]
- Plasminogen Activator Inhibitor-1 Measurement [NCIt concept]
- SERPINE1 Gene [NCIt concept]
- SERPINE1 wt Allele [NCIt concept]
- Serpin peptidase inhibitor, clade e (nexin, plasminogen activator inhibitor type 1), member 1 [OMIM gene]
- serpin family E member 1 [ORDO Gene]
Currated CISMeF NLP mapping
- Plasminogen Activator Inhibitor 1 [NCIt concept]
- Plasminogen activator inhibitor 1 [LOINC component]
- Plasminogen activator inhibitor-1 (substance) [SNOMED CT concept]
- plasminogen activator inhibitor-1 [SNOMED Notion]
Indexing information
- AZ3976 [MeSH Supplementary Concept]
- S 35225 [MeSH Supplementary Concept]
- paionin-1 [MeSH Supplementary Concept]
- tiplaxtinin [MeSH Supplementary Concept]
Pharmacological action(s)
- serine proteinase inhibitors [MeSH Descriptor]
Record concept(s)
- plasminogen activator inhibitor 1 [MeSH concept]
Related MeSH Supplementary Concept(s)
- SERPINE1 protein, human [MeSH Supplementary Concept]
- SERPINe1 protein, zebrafish [MeSH Supplementary Concept]
- Serpine1 protein, rat [MeSH Supplementary Concept]
- plasminogen activator Inhibitor-1 deficiency [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Plasminogen activator inhibitor 1 [LOINC component]
- Plasminogen activator inhibitor-1 (substance) [SNOMED CT concept]
- plasminogen activator inhibitor-1 [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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