MeSH definition : A muscle protein localized in surface membranes which is the product of the Duchenne/Becker
muscular dystrophy gene. Individuals with Duchenne muscular dystrophy usually lack
dystrophin completely while those with Becker muscular dystrophy have dystrophin of
an altered size. It shares features with other cytoskeletal proteins such as SPECTRIN
and alpha-actinin but the precise function of dystrophin is not clear. One possible
role might be to preserve the integrity and alignment of the plasma membrane to the
myofibrils during muscle contraction and relaxation. MW 400 kDa.;
MeSH annotation : a muscle protein: see MeSH definition for relation to musc dystrophy; /biosyn /drug
eff /physiol /ultrastruct permitted;
Wikipedia link : https://en.wikipedia.org/wiki/Dystrophin;
A muscle protein localized in surface membranes which is the product of the Duchenne/Becker
muscular dystrophy gene. Individuals with Duchenne muscular dystrophy usually lack
dystrophin completely while those with Becker muscular dystrophy have dystrophin of
an altered size. It shares features with other cytoskeletal proteins such as SPECTRIN
and alpha-actinin but the precise function of dystrophin is not clear. One possible
role might be to preserve the integrity and alignment of the plasma membrane to the
myofibrils during muscle contraction and relaxation. MW 400 kDa.
http://www.umd.be/DMD/ France French database dystrophin muscular dystrophy, duchenne