Preferred Label : mice, inbred mdx;
MeSH definition : A strain of mice arising from a spontaneous MUTATION (mdx) in inbred C57BL mice. This
mutation is X chromosome-linked and produces viable homozygous animals that lack the
muscle protein DYSTROPHIN, have high serum levels of muscle ENZYMES, and possess histological
lesions similar to human MUSCULAR DYSTROPHY. The histological features, linkage, and
map position of mdx make these mice a worthy animal model of DUCHENNE MUSCULAR DYSTROPHY.;
MeSH synonym : inbred mdx mouse; mdx mice; inbred mdx mice; mouse, inbred mdx; mice, mdx; mouse, mdx; mdx mouse;
CISMeF synonym : mdx mice, inbred; mdx mouse, inbred;
MeSH annotation : NIM with no qualifiers when experimental animal; check the tag MICE; NIM with no qualifiers when experimental animal;
Origin ID : D018101;
UMLS CUI : C0206535;
Allowable qualifiers
- Record concept(s)
- See also
- Semantic type(s)
A strain of mice arising from a spontaneous MUTATION (mdx) in inbred C57BL mice. This
mutation is X chromosome-linked and produces viable homozygous animals that lack the
muscle protein DYSTROPHIN, have high serum levels of muscle ENZYMES, and possess histological
lesions similar to human MUSCULAR DYSTROPHY. The histological features, linkage, and
map position of mdx make these mice a worthy animal model of DUCHENNE MUSCULAR DYSTROPHY.
