ofloxacin - CISMeF

Preferred Label : ofloxacin;

Obsolete resource : false;

MeSH definition : A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.;

MeSH synonym : Ofloxacine;

CISMeF synonym : 118120-51-7 (Ofloxacin hydrochloride);

MeSH hyponym : ofloxacin hydrochloride; tarivid; Hoe-280; DL-8280; ORF-28489; Ru-43280; DR-3355; ORF 28489; ORF28489; DR 3355; DR3355; Hoe 280; Hoe280; Ru 43280; Ru43280; DL 8280; DL8280;

MeSH CAS label : ( /-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7- -oxo-7H-pyrido(1,2,3-de)- -1,4-benzoxazine-6-carboxylic acid;

MeSH Related Number : ofloxacin hydrochloride; 100986-86-5 ((R)-isomer); 118120-51-7 (HCl); 82419-36-1 (Ofloxacin); 86784-41-0 (cpd w/o isomeric designation); I2UWV315WA;

Registry Number MeSH : 82419-36-1;

Related CAS MeSH : 100986-85-4 (Levofloxacin); I2UWV315WA (Ofloxacin hydrochloride);

Wikipedia link : https://en.wikipedia.org/wiki/Ofloxacin;

Is substance : O;

UNII : A4P49JAZ9H;

InChIKey : GSDSWSVVBLHKDQ-UHFFFAOYSA-N;

Details

Origin ID

D015242;

UMLS CUI

C0028902;

ATC code(s)
- ofloxacin [ATC Code]
ATC code(s)
- ofloxacin [ATC Code]
- ofloxacin [ATC Code]
- ofloxacin [ATC Code]
- ofloxacin and ornidazole [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- ofloxacin [Substance BNPC]
Currated CISMeF NLP mapping
- Ofloxacin [ICD-11 Extension code]
- Ofloxacin [LOINC component]
- Ofloxacin [NCIt concept]
- Ofloxacin (substance) [SNOMED CT concept]
- ofloxacin [SNOMED Notion]
Pharmacological action(s)
- Cytochrome P-450 CYP1A2 Inhibitors [MeSH Descriptor]
- anti-bacterial agents [MeSH Descriptor]
- anti-infective agents, urinary [MeSH Descriptor]
- antineoplastic agents [MeSH Descriptor]
- topoisomerase II inhibitors [MeSH Descriptor]
Record concept(s)
- DL-8280 [MeSH concept]
- DR-3355 [MeSH concept]
- Hoe-280 [MeSH concept]
- ORF-28489 [MeSH concept]
- Ru-43280 [MeSH concept]
- ofloxacin [MeSH concept]
- ofloxacin hydrochloride [MeSH concept]
- tarivid [MeSH concept]
Related MeSH Supplementary Concept(s)
- 3-fluoromethyl ofloxacin [MeSH Supplementary Concept]
- R 71762 [MeSH Supplementary Concept]
- antofloxacin [MeSH Supplementary Concept]
- desmethylofloxacin [MeSH Supplementary Concept]
- ofloxacin N-oxide [MeSH Supplementary Concept]
- ofloxacin O-glucuronide [MeSH Supplementary Concept]
- ofloxacin pivaloyloxymethyl ester [MeSH Supplementary Concept]
See also (suggested by CISMeF)
- anti-bacterial agents [MeSH Descriptor]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Ofloxacin [LOINC component]
- Ofloxacin [ICD-11 Extension code]
- Ofloxacin [NCIt concept]
- Ofloxacin (substance) [SNOMED CT concept]
- Product containing ofloxacin (medicinal product) [SNOMED CT concept]
- ofloxacin [ATC Code]
- ofloxacin [ATC Code]
- ofloxacin [ATC Code]
- ofloxacin [Substance BNPC]
- ofloxacin [SNOMED Notion]
Validated automatic mappings to BTNT
- Levofloxacin (substance) [SNOMED CT concept]
- ofloxacin [ATC Code]
- ofloxacin [ATC Code]
- ofloxacin [ATC Code]

Keyword's position in hierarchy(ies) :

Main resources

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