Ofloxacin - CISMeF

Preferred Label : Ofloxacin;

NCIt synonyms : 9-Fluoro-2,3-Dihydro-3-Methyl-10-(4-Methyl-1-Piperazinyl)-7-Oxo-7H-Pyrido(1,2,3-de)(1,4)benzoxazine-6-Carboxylic Acid, DL-;

NCIt definition : A fluoroquinolone antibacterial antibiotic. Ofloxacin binds to and inhibits bacterial topoisomerase II (DNA gyrase) and topoisomerase IV, enzymes involved in DNA replication and repair, resulting in cell death in sensitive bacterial species. (NCI04);

Alternative definition : NCI-GLOSS: An antibiotic drug used to treat infection. It belongs to the family of drugs called quinolone antibiotics.;

UNII : A4P49JAZ9H;

InChIKey : GSDSWSVVBLHKDQ-UHFFFAOYSA-N;

CAS number : 82419-36-1; 83380-47-6;

Drug name : Ocuflox; Floxin;

Molecule name : DL-8280; HOE 280;

Chemical formula : C18H20FN3O4;

NSC code : 727071;

ChEBI ID : CHEBI:7731;

Codes from synonyms : CDR0000045567;

Details

Origin ID

C712;

UMLS CUI

C0028902;

Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Ofloxacin [ICD-11 Extension code]
- Ofloxacin [LOINC component]
- Ofloxacin (substance) [SNOMED CT concept]
- Product containing ofloxacin (medicinal product) [SNOMED CT concept]
- ofloxacin [ATC Code]
- ofloxacin [ATC Code]
- ofloxacin [ATC Code]
- ofloxacin [Substance BNPC]
- ofloxacin [MeSH concept]
- ofloxacin [MeSH Descriptor]
- ofloxacin [SNOMED Notion]
Validated automatic mappings to BTNT
- ofloxacin [ATC Code]
- ofloxacin [ATC Code]
- ofloxacin [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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