tacrine - CISMeF

Preferred Label : tacrine;

MeSH definition : A cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders.;

MeSH synonym : tetrahydroaminoacridine; 1,2,3,4-tetrahydro-9-acridinamine; 9-amino-1,2,3,4-tetrahydroacridine; 1,2,3,4-tetrahydroaminoacridine;

CISMeF synonym : 1684-40-8 (Tacrine hydrochloride); woods brand of tacrine hydrochloride; OTL pharm brand of tacrine hydrochloride; parke davis brand of tacrine hydrochloride; horizon brand of tacrine hydrochloride;

MeSH hyponym : tenakrin; cognex; THA; Tacrine Hydrochloride; romotal;

MeSH CAS label : 9-Acridinamine, 1,2,3,4-tetrahydro-;

MeSH Related Number : tacrine hydrochloride; 1684-40-8 (HCl); 321-64-2 (Tacrine); 4966RNG0BU;

Registry Number MeSH : 321-64-2;

Related CAS MeSH : 4966RNG0BU (Tacrine hydrochloride);

Wikipedia link : https://en.wikipedia.org/wiki/Tacrine;

Codes EINECS : 206-291-2;

Is substance : O;

UNII : 4VX7YNB537;

InChIKey : YLJREFDVOIBQDA-UHFFFAOYSA-N;

Details

Origin ID

D013619;

UMLS CUI

C0039245;

ATC code(s)
- tacrine [ATC Code]
ATC code(s)
- tacrine [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- tacrine [Substance BNPC]
False automatic mappings
- Thai Language [NCIt concept]
- Thailand [NCIt concept]
- thromboxane A synthase 1 [ORDO Gene]
Pharmacological action(s)
- cholinesterase inhibitors [MeSH Descriptor]
- nootropic agents [MeSH Descriptor]
- parasympathomimetics [MeSH Descriptor]
- peripheral nervous system agents [MeSH Descriptor]
Record concept(s)
- THA [MeSH concept]
- Tacrine Hydrochloride [MeSH concept]
- cognex [MeSH concept]
- romotal [MeSH concept]
- tacrine [MeSH concept]
- tenakrin [MeSH concept]
Related MeSH Supplementary Concept(s)
- (9-amino-5,6,7,8-tetrahydroacridin-4-yl)methanol [MeSH Supplementary Concept]
- 1,7-N-heptylene-bis-9,9'-amino-1,2,3,4-tetrahydroacridine [MeSH Supplementary Concept]
- 2-hydroxytacrine [MeSH Supplementary Concept]
- 2-tert-butyl-9-amino-1,2,3,4-tetrahydroacridine [MeSH Supplementary Concept]
- 3-hydroxytacrine [MeSH Supplementary Concept]
- 4-hydroxytacrine [MeSH Supplementary Concept]
- 5,6-dimethoxy-2-(6-((1,2,3,4-tetrahydroacridin-9-yl)amino)hexyl)benzo(d)(1,2)selenazol-3(2H)-one [MeSH Supplementary Concept]
- 6-chlorotacrine [MeSH Supplementary Concept]
- 6-hydroxy-4-oxo-N-(10-((1,2,3,4-tetrahydroacridin-9-yl)amino)decyl)-4H-chromene-2-carboxamide [MeSH Supplementary Concept]
- 7-bromotacrine [MeSH Supplementary Concept]
- 7-methoxy-N-(2-(4-(3-methylbenzyl)piperazine-1-yl)ethyl)-1,2,3,4-tetrahydroacridin-9-amine [MeSH Supplementary Concept]
- 7-methoxytacrine [MeSH Supplementary Concept]
- 9-(3-(2-nitro-1-imidazolyl)propylamino)-1,2,3,4-tetrahydroacridine [MeSH Supplementary Concept]
- 9-amino-10-methyl-1,2,3,4-tetrahydroacridine [MeSH Supplementary Concept]
- 9-hydroxylamine-1,2,3,4-tetrahydroacridine [MeSH Supplementary Concept]
- N-(2-(4-(3-bromobenzyl)piperazine-1-yl)ethyl)-7-methoxy-1,2,3,4-tetrahydroacridin-9-amine [MeSH Supplementary Concept]
- N-(3-((6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino)propyl)-5-(4-chlorophenyl)-1,2,3,4-tetrahydrobenzo(h)(1,6)naphthyridine-9-carboxamide [MeSH Supplementary Concept]
- N-(5-((6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino)pentyl)-2-(4-(5,6,7-trimethoxy-4-oxo-4H-chromen-2-yl)phenoxy)acetamide [MeSH Supplementary Concept]
- N-butyramide-tacrine [MeSH Supplementary Concept]
- N-ethyltacrine [MeSH Supplementary Concept]
- N-hexyl-7-methoxytacrine [MeSH Supplementary Concept]
- N-methyltacrine [MeSH Supplementary Concept]
- SCR1693 [MeSH Supplementary Concept]
- THB 013 [MeSH Supplementary Concept]
- TZ2PA6 compound [MeSH Supplementary Concept]
- bis(3)-cognitin [MeSH Supplementary Concept]
- bis(heptyl)cognitin [MeSH Supplementary Concept]
- bis(propyl)cognitin [MeSH Supplementary Concept]
- centbucridine [MeSH Supplementary Concept]
- ethyl 5-amino-6,7,8,9-tetrahydro-2-methyl-4-phenylbenzo(1,8)naphthyridine-3-carboxylate [MeSH Supplementary Concept]
- lipocrine [MeSH Supplementary Concept]
- tacrine-6-ferulic acid [MeSH Supplementary Concept]
- tacrine-8-hydroxyquinoline [MeSH Supplementary Concept]
- velnacrine [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Product containing tacrine (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing tacrine (medicinal product) [SNOMED CT concept]
- Tacrine [ICD-11 Extension code]
- Tacrine [NCIt concept]
- Tacrine [LOINC component]
- Tacrine (substance) [SNOMED CT concept]
- tacrine [ATC Code]
- tacrine [Substance BNPC]
Validated automatic mappings to BTNT
- 1,2,3,4-tetrahydroacridin-9-amine monohydrochloride [Substance BNPC]
- Tacrine Hydrochloride [NCIt concept]
- Tacrine hydrochloride (substance) [SNOMED CT concept]
- tacrine [ATC Code]

Keyword's position in hierarchy(ies) :

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