velnacrine - CISMeF

Preferred Label : velnacrine;

MeSH note : RN given refers to ( -)-isomer; RN for cpd without isomeric designation not available 8/88; structure in first source; potential Alzheimer's disease drug but trial halted due to abnormal liver tests;

CISMeF synonym : HP 029;

MeSH synonym : 1-hydroxytacrine; 1,2,3,4-tetrahydro-9-aminoacridine-1-ol; 9-ATHCO; 9-amino-1,2,3,4-tetrahydroacridin-1-ol;

MeSH hyponym : 1,2,3,4-tetrahydro-9-aminoacridin-1-ol maleate; HP-029;

MeSH Related Number : velnacrine maleate; 104675-29-8 (velnacrine); 112964-98-4 (former RN); 112964-99-5 (former RN, maleate); 118909-22-1 (maleate); YY1JW04JCB;

Registry Number MeSH : 104675-29-8;

Related CAS MeSH : 118909-22-1 (velnacrine maleate);

related registry number list (CISMeF) : 112964-98-4 (former RN); 112964-99-5 (former RN, maleate); 118909-22-1 (maleate);

Is substance : O;

UNII : Y2P6NV151K;

InChIKey : HLVVITIHAZBPKB-UHFFFAOYSA-N;

Details

Origin ID

C056424;

UMLS CUI

C0078151;

Automatic exact mappings (from CISMeF team)
- Velnacrine Maleate [NCIt concept]
Currated CISMeF NLP mapping
- Velnacrine [NCIt concept]
MeSH indexing information
- alzheimer disease [MeSH Descriptor]
MeSH term(s) associated for indexing
- tacrine [MeSH Descriptor]
Pharmacological action(s)
- cholinesterase inhibitors [MeSH Descriptor]
Record concept(s)
- HP 029 [MeSH concept]
- velnacrine [MeSH concept]
- velnacrine maleate [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Velnacrine [NCIt concept]

Keyword's position in hierarchy(ies) :

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