quinidine - CISMeF

Preferred Label : quinidine;

MeSH definition : An optical isomer of quinine, extracted from the bark of the CHINCHONA tree and similar plant species. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. It prolongs cellular ACTION POTENTIALS, and decreases automaticity. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission.;

MeSH synonym : chinidin;

CISMeF synonym : apotex brand of quinidine sulfate; robins brand of quinidine sulfate; nelson brand of quinidine sulfate; fawns & McAllan brand of quinidine sulfate;

MeSH hyponym : quinidex; quincardine; quinora; adaquin; Apo-Quinidine; Quinidine Sulfate; Apo Quinidine; Sulfate, Quinidine;

MeSH CAS label : Cinchonan-9-ol, 6'-methoxy-, (9S)-;

MeSH Related Number : 56-54-2 (Quinidine); quinidine sulfate; J13S2394HE;

Registry Number MeSH : 56-54-2;

Related CAS MeSH : J13S2394HE (Quinidine sulfate);

Wikipedia link : https://en.wikipedia.org/wiki/Quinidine;

Is substance : O;

UNII : ITX08688JL;

InChIKey : LOUPRKONTZGTKE-LHHVKLHASA-N;

Details

Origin ID

D011802;

UMLS CUI

C0034414;

ATC code(s)
- quinidine [ATC Code]
- quinidine, combinations excl. psycholeptics [ATC Code]
- quinidine, combinations with psycholeptics [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Chinidin (e) [ICD-11 Extension code]
- quinidine [EMDN type]
Currated CISMeF NLP mapping
- Quinidine [ICD-11 Extension code]
- Quinidine [ICHI extension code]
- Quinidine [SMS substance]
- Quinidine [NCIt concept]
- Quinidine (substance) [SNOMED CT concept]
- quiNIDine [LOINC component]
- quinidine [SNOMED Notion]
- quinidine [medical devices type]
Pharmacological action(s)
- Cytochrome P-450 CYP2D6 Inhibitors [MeSH Descriptor]
- Voltage-Gated sodium channel blockers [MeSH Descriptor]
- adrenergic alpha-antagonists [MeSH Descriptor]
- anti-arrhythmia agents [MeSH Descriptor]
- antimalarials [MeSH Descriptor]
- muscarinic antagonists [MeSH Descriptor]
Record concept(s)
- Apo-Quinidine [MeSH concept]
- Quinidine Sulfate [MeSH concept]
- adaquin [MeSH concept]
- quincardine [MeSH concept]
- quinidex [MeSH concept]
- quinidine [MeSH concept]
- quinora [MeSH concept]
Related MeSH Supplementary Concept(s)
- 10,11-dihydroxydihydroquinidine N-oxide [MeSH Supplementary Concept]
- 2'-oxoquinidinone [MeSH Supplementary Concept]
- 3-hydroxy-10,11-dihydroquinidine [MeSH Supplementary Concept]
- 3-hydroxydihydroquinidine [MeSH Supplementary Concept]
- 3-hydroxyhydroquinidine [MeSH Supplementary Concept]
- 3-hydroxyquinidine [MeSH Supplementary Concept]
- 7'-trifluoromethyldihydrocinchonidine [MeSH Supplementary Concept]
- 9-amino-9-deoxy-epi-hydroquinine [MeSH Supplementary Concept]
- dextromethorphan - quinidine combination [MeSH Supplementary Concept]
- hydroquinidine [MeSH Supplementary Concept]
- isoleucine-quinidine conjugate [MeSH Supplementary Concept]
- phenobarbital quinidine [MeSH Supplementary Concept]
- phenrytmat [MeSH Supplementary Concept]
- quinidine arabogalactane sulfate [MeSH Supplementary Concept]
- quinidine bisulfate [MeSH Supplementary Concept]
- quinidine gluconate [MeSH Supplementary Concept]
- quinidine polygalacturonate [MeSH Supplementary Concept]
- quinidine, verapamil drug combination [MeSH Supplementary Concept]
- quinidine-N-oxide [MeSH Supplementary Concept]
- quinidinium [MeSH Supplementary Concept]
- tert-butylcarbamoylquinidine [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing quinidine (medicinal product) [SNOMED CT concept]
- Quinidine [ICD-11 Extension code]
- Quinidine [NCIt concept]
- Quinidine (substance) [SNOMED CT concept]
- quiNIDine [LOINC component]
- quinidine [ATC Code]
- quinidine [SNOMED Notion]
Validated automatic mappings to BTNT
- Quinidine Sulfate [NCIt concept]
- Quinidine sulfate [SMS substance]
- Quinidine sulfate (substance) [SNOMED CT concept]
- Quinidine sulfate anhydrous [Substance BNPC]
- quinidine [ATC Code]
- quinidine sulfate [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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